Benomyl

Benomyl

SCHEMBL542435

CCCCNC(=O)n1c(NC(=O)OC)nc2ccccc21.CCCSP(=O)(OCC)SCCC

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.75
ALDH1A1 P00352 1/20 0.75
ASAH1 Q13510 7/20 0.47
IRAK4 Q9NWZ3 2/20 0.39
KMT2A Q03164 3/20 0.39
NPSR1 Q6W5P4 2/20 0.39
KDM4E B2RXH2 2/20 0.39
MEN1 O00255 2/20 0.39
USP2 O75604 1/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
SAE1 Q9UBE0 1/20 0.37
UBA2 Q9UBT2 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
CNR2 P34972 1/20 0.35
GAA P10253 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
ADORA2A P29274 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benomyl SCHEMBL28422686 0.87 TSHR (0.92) TSHRALDH1A1ASAH1IRAK4KMT2A
Benomyl SCHEMBL29379464 0.87 TSHR (1.00) TSHRALDH1A1ASAH1IRAK4KMT2A
Benomyl SCHEMBL15681 0.87 TSHR (1.00) TSHRALDH1A1ASAH1IRAK4KMT2A
Benomyl SCHEMBL8379451 0.87 TSHR (1.00) TSHRALDH1A1ASAH1IRAK4KMT2A
Benomyl SCHEMBL3962065 0.86 TSHR (0.98) TSHRALDH1A1ASAH1IRAK4KMT2A
Benomyl SCHEMBL28721488 0.84 TSHR (0.94) TSHRALDH1A1ASAH1IRAK4KMT2A
Benomyl SCHEMBL27841656 0.84 TSHR (0.94) TSHRALDH1A1ASAH1IRAK4KMT2A
Benomyl SCHEMBL23632884 0.83 TSHR (0.92) TSHRALDH1A1ASAH1IRAK4KMT2A
Benomyl SCHEMBL6912357 0.83 TSHR (0.92) TSHRALDH1A1ASAH1IRAK4KMT2A
SCHEMBL9578770 0.83 TSHR (0.91) TSHRALDH1A1ASAH1IRAK4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130231299-A1 METHODS FOR REDUCING NEMATODE DAMAGE SYNGENTA CROP PROTECTION LLC (US) 2013-09-05 US claimed
EP-1850662-B1 METHOD OF IMPROVING NEMATODE TOLERANT OR RESISTANT PLANT GROWTH SYNGENTA PARTICIPATIONS AG (CH) 2012-02-08 EP claimed
EP-2269450-A2 Method of improving nematode tolerant or resistant plant growth Syngenta Participations AG. (CH) 2011-01-05 EP claimed
US-20090054234-A1 Method of Improving Nematode or Resistant Plant Growth SYNGENTA CROP PROTECTION, INC. (US) 2009-02-26 US claimed
US-20080254013-A1 Using chelate agent and macrocyclic lactone to prevent parasitic worm infection of plants SYNGENTA CROP PROTECTION, INC. (US) 2008-10-16 US claimed
EP-1850662-A2 METHOD OF IMPROVING NEMATODE TOLERANT OR RESISTANT PLANT GROWTH Syngeta Participations AG (CH) 2007-11-07 EP claimed
EP-1765079-A1 METHODS OF REDUCING NEMATODE DAMAGE Syngeta Participations AG (CH) 2007-03-28 EP claimed
WO-2006089733-A2 METHOD OF IMPROVING NEMATODE TOLERANT OR RESISTANT PLANT GROWTH SYNGENTA PARTICIPATIONS AG (CH) 2006-08-31 WO claimed
WO-2005120232-A1 METHODS OF REDUCING NEMATODE DAMAGE SYNGENTA PARTICIPATIONS AG (CH) 2005-12-22 WO claimed
US-10542747-B2 Plant irrigation methods with 1-MCP SYNGENTA PARTICIPATIONS AG (CH) 2020-01-28 US disclosed
EP-2592923-B1 PLANT IRRIGATION METHODS WITH 1-MCP SYNGENTA PARTICIPATIONS AG (CH) 2019-07-31 EP disclosed
US-20180184646-A1 FUZZY COTTON SEEDS COMPRISING AN AQUEOUS POLYURETHANE COATING BAYER CROPSCIENCE LP 2018-07-05 US disclosed
US-9980479-B2 Method of reducing nematode damage SYNGENTA CROP PROTECTION, LLC (US) 2018-05-29 US disclosed
US-9861105-B2 Methods and compositions for controlling nematode pests SYNGENTA PARTICIPATIONS AG (CH) 2018-01-09 US disclosed
EP-1925205-A1 Plant propagation material treatment nematicides Sygenta Participations AG. (CH) 2008-05-28 EP disclosed
EP-1925204-A1 Plant propagation material treatment nematicides Syngeta Participations AG (CH) 2008-05-28 EP disclosed
EP-1850662-A2 METHOD OF IMPROVING NEMATODE TOLERANT OR RESISTANT PLANT GROWTH Syngeta Participations AG (CH) 2007-11-07 EP disclosed
EP-1765079-A1 METHODS OF REDUCING NEMATODE DAMAGE Syngeta Participations AG (CH) 2007-03-28 EP disclosed
WO-2006089733-A2 METHOD OF IMPROVING NEMATODE TOLERANT OR RESISTANT PLANT GROWTH SYNGENTA PARTICIPATIONS AG (CH) 2006-08-31 WO disclosed
WO-2005120232-A1 METHODS OF REDUCING NEMATODE DAMAGE SYNGENTA PARTICIPATIONS AG (CH) 2005-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054234-A1 Method of Improving Nematode or Resistant Plant Growth GAP43, CAT, NPEPPS TSHR 1504/4885ALDH1A1 3131/4885ASAH1 2101/4885
US-10542747-B2 Plant irrigation methods with 1-MCP CCL2, CCL11, CCL5 TSHR 4604/4885ALDH1A1 1159/4885ASAH1 341/4885
US-20080254013-A1 Using chelate agent and macrocyclic lactone to prevent parasitic worm infection of plants GMNN, DDT, CTSA TSHR 2065/4885ALDH1A1 3768/4885ASAH1 2009/4885
US-20130231299-A1 METHODS FOR REDUCING NEMATODE DAMAGE PCNA, CAT, GMNN TSHR 3507/4885ALDH1A1 2491/4885ASAH1 1934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.