Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.50 |
| ▸ | CDK2 | P24941 | 2/20 | 0.50 |
| ▸ | CDK9 | P50750 | 2/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.50 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.50 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | TRPV3 | Q8NET8 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5359412 | 1.00 | CCNT1 (0.50) | CCNT1CCNA2CDK2CDK9CDK5 | |
| SCHEMBL5766910 | 0.89 | CA1 (0.49) | CCNT1CCNA2CDK2CDK9CDK5 | |
| SCHEMBL1734544 | 0.81 | CA12 (0.46) | CA12CA1MMP2MEN1KMT2A | |
| SCHEMBL14509044 | 0.81 | CA12 (0.46) | CA12CA1MMP2MEN1KMT2A | |
| SCHEMBL1734546 | 0.81 | CA12 (0.46) | CA12CA1MMP2MEN1KMT2A | |
| SCHEMBL8996214 | 0.80 | KIF11 (0.45) | CA12CA1MMP2MEN1KMT2A | |
| SCHEMBL1937094 | 0.80 | KIF11 (0.45) | CA12CA1MMP2MEN1KMT2A | |
| SCHEMBL3265463 | 0.80 | KIF11 (0.45) | CA12CA1MMP2MEN1KMT2A | |
| SCHEMBL5129528 | 0.79 | CA12 (0.41) | CCNT1CCNA2CDK2CDK9CDK5 | |
| SCHEMBL5357329 | 0.79 | CA12 (0.41) | CCNT1CCNA2CDK2CDK9CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223870-B2 | Methods for preparing N-arylated oxazolidinones via a copper catalyzed cross coupling reaction | PFIZER INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223870-B2 | Methods for preparing N-arylated oxazolidinones via a copper catalyzed cross coupling reaction | PFIZER INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-20070049759-A1 | Methods for Preparing N-Arylated Oxazolidinones Via A Copper Catalyzed Cross Coupling | PFIZER INC | 2007-03-01 | — | — | US | disclosed |
| US-20070049759-A1 | Methods for Preparing N-Arylated Oxazolidinones Via A Copper Catalyzed Cross Coupling | PFIZER INC | 2007-03-01 | — | — | US | disclosed |
| US-20070049759-A1 | Methods for Preparing N-Arylated Oxazolidinones Via A Copper Catalyzed Cross Coupling | PFIZER INC | 2007-03-01 | — | — | US | disclosed |
| EP-1562916-A1 | METHODS FOR PREPARING N-ARYLATED OXAZOLIDINONES VIA A COPPER CATALYZED CROSS COUPLING REACTION | Pfizer Products Inc. (US) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004039788-A1 | METHODS FOR PREPARING N-ARYLATED OXAZOLIDINONES VIA A COPPER CATALYZED CROSS COUPLING REACTION | PFIZER PRODUCTS INC. (US) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049759-A1 | Methods for Preparing N-Arylated Oxazolidinones Via A Copper Catalyzed Cross Coupling | AOC2, SOD1, AOC3 | CCNT1 331/4885CCNA2 960/4885CDK2 214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.