Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4883674 | 0.91 | ALDH1A1 (0.42) | EDNRAEDNRB | |
| SCHEMBL5186159 | 0.91 | EDNRA (0.52) | EDNRAEDNRB | |
| Hydrochloric Acid SCHEMBL4883670 | 0.90 | ALDH1A1 (0.41) | EDNRAEDNRB | |
| SCHEMBL4592011 | 0.86 | EDNRB (0.52) | EDNRAEDNRB | |
| SCHEMBL4591054 | 0.86 | EDNRA (0.52) | EDNRAEDNRB | |
| SCHEMBL4591109 | 0.83 | ALDH1A1 (0.45) | EDNRAEDNRB | |
| SCHEMBL4592550 | 0.83 | KMT2A (0.50) | EDNRAEDNRB | |
| Hydrochloric Acid SCHEMBL4591112 | 0.82 | ESR1 (0.45) | — | |
| SCHEMBL4591982 | 0.82 | ALDH1A1 (0.49) | — | |
| Hydrochloric Acid SCHEMBL4591984 | 0.81 | ALDH1A1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070248672-A1 | Indole and Azaindole Derivatives with Antitumor Action | NIKEM RESEARCH S.R.L. (IT) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070248672-A1 | Indole and Azaindole Derivatives with Antitumor Action | IDO1, IDO2, INMT | EDNRA 662/4885EDNRB 1151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.