Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 4/20 | 0.38 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.33 |
| ▸ | GCG | P01275 | 3/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16543455 | 0.85 | GCG (0.35) | SLC34A1KIF11EGLN1RPS6KA5GCG | |
| SCHEMBL12075257 | 0.78 | ALKBH2 (0.54) | EPHX2HDAC4EGLN1GRM4ALKBH2 | |
| SCHEMBL16566376 | 0.76 | HSP90AA1 (0.41) | EGLN1RPS6KA5TGFBR1IRAK4GRM4 | |
| SCHEMBL16547536 | 0.76 | ALDH1A1 (0.48) | CYP46A1EGLN1RPS6KA5IRAK4ALKBH2 | |
| SCHEMBL30238265 | 0.76 | KDM4E (0.39) | SLC34A1CYP46A1EPHX2GRIN1GRIN2B | |
| SCHEMBL28606131 | 0.74 | TRPV1 (0.43) | SLC34A1EPHX2RPS6KA5GRM4 | |
| SCHEMBL11900004 | 0.73 | EPHX2 (0.44) | KIF11EPHX2HDAC4GCGREGLN1 | |
| SCHEMBL11899762 | 0.73 | HDAC4 (0.42) | KIF11EPHX2HDAC4GRIN1GRIN2B | |
| SCHEMBL21491621 | 0.73 | KDM4E (0.46) | SLC34A1KIF11HDAC4EGLN1 | |
| SCHEMBL20075623 | 0.72 | SLC34A1 (0.45) | SLC34A1EPHX2HDAC4EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153725-A1 | HERBICIDALLY ACTIVE 4-(4-TRIFLUORMETHYL-6-CYCLOROPYLPYRAZOLYL)PYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2022-05-19 | — | — | US | disclosed |
| US-7312180-B2 | Substituted 4-(4-trifluoromethylpyrazolyl)pyrimidines | BAYER CROPSCIENCE GMBH (DE) | 2007-12-25 | — | — | US | disclosed |
| US-7312180-B2 | Substituted 4-(4-trifluoromethylpyrazolyl)pyrimidines | BAYER CROPSCIENCE GMBH (DE) | 2007-12-25 | — | — | US | disclosed |
| US-7312180-B2 | Substituted 4-(4-trifluoromethylpyrazolyl)pyrimidines | BAYER CROPSCIENCE GMBH (DE) | 2007-12-25 | — | — | US | disclosed |
| CN-1929738-A | Substituted 4- (4-trifluoromethylpyrazolyl) pyrimidines as herbicides | BAYER CROPSCIENCE GMBH (DE) | 2007-03-14 | — | — | CN | disclosed |
| CN-1929738-A | Substituted 4- (4-trifluoromethylpyrazolyl) pyrimidines as herbicides | BAYER CROPSCIENCE GMBH (DE) | 2007-03-14 | — | — | CN | disclosed |
| EP-1725103-A1 | SUBSTITUTED 4-(4-TRIFLUOROMETHYLPYRAZOLYL)-PYRIMIDINES SERVING AS HERBICIDES | Bayer CropScience GmbH (DE) | 2006-11-29 | — | — | EP | disclosed |
| EP-1725103-A1 | SUBSTITUTED 4-(4-TRIFLUOROMETHYLPYRAZOLYL)-PYRIMIDINES SERVING AS HERBICIDES | Bayer CropScience GmbH (DE) | 2006-11-29 | — | — | EP | disclosed |
| EP-1725103-A1 | SUBSTITUTED 4-(4-TRIFLUOROMETHYLPYRAZOLYL)-PYRIMIDINES SERVING AS HERBICIDES | Bayer CropScience GmbH (DE) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005089551-A1 | SUBSTITUTED 4-(4-TRIFLUOROMETHYLPYRAZOLYL)-PYRIMIDINES SERVING AS HERBICIDES | BAYER CROPSCIENCE GMBH (DE) | 2005-09-29 | — | — | WO | disclosed |
| WO-2005089551-A1 | SUBSTITUTED 4-(4-TRIFLUOROMETHYLPYRAZOLYL)-PYRIMIDINES SERVING AS HERBICIDES | BAYER CROPSCIENCE GMBH (DE) | 2005-09-29 | — | — | WO | disclosed |
| WO-2005089551-A1 | SUBSTITUTED 4-(4-TRIFLUOROMETHYLPYRAZOLYL)-PYRIMIDINES SERVING AS HERBICIDES | BAYER CROPSCIENCE GMBH (DE) | 2005-09-29 | — | — | WO | disclosed |
| US-20050209106-A1 | Substituted 4-(4-trifluoromethylpyrazolyl)pyrimidines | BAYER CROPSCIENCE GMBH (DE) | 2005-09-22 | — | — | US | disclosed |
| US-20050209106-A1 | Substituted 4-(4-trifluoromethylpyrazolyl)pyrimidines | BAYER CROPSCIENCE GMBH (DE) | 2005-09-22 | — | — | US | disclosed |
| US-20050209106-A1 | Substituted 4-(4-trifluoromethylpyrazolyl)pyrimidines | BAYER CROPSCIENCE GMBH (DE) | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209106-A1 | Substituted 4-(4-trifluoromethylpyrazolyl)pyrimidines | CYP4X1, DDT, CYP4F3 | SLC34A1 2304/4885CYP46A1 3193/4885KIF11 3653/4885 |
| US-20220153725-A1 | HERBICIDALLY ACTIVE 4-(4-TRIFLUORMETHYL-6-CYCLOROPYLPYRAZOLYL)PYRIMIDINES | DDT, CYP4X1, CYP4Z1 | SLC34A1 2209/4885CYP46A1 3340/4885KIF11 2467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.