Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.75 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | NQO1 | P15559 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | CASP7 | P55210 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38652382 | 0.93 | MAOB (0.73) | MAOBNPC1NQO1MAPTKDM4E | |
| SCHEMBL5141444 | 0.92 | MAOB (0.71) | MAOBNPC1NQO1MAPTKDM4E | |
| SCHEMBL15103561 | 0.87 | CA1 (0.63) | MAOBNPC1NQO1MAPTKDM4E | |
| SCHEMBL11485562 | 0.86 | MAOB (1.00) | MAOBNPC1NQO1MAPTKDM4E | |
| SCHEMBL28085675 | 0.85 | MAOB (0.65) | MAOBNPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL7123957 | 0.84 | NPC1 (0.80) | MAOBNPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL6276172 | 0.83 | NQO1 (0.73) | MAOBNPC1NQO1MAPTKDM4E | |
| SCHEMBL5142288 | 0.82 | MAOB (0.65) | MAOBNPC1NQO1MAPTKDM4E | |
| SCHEMBL7117813 | 0.82 | ALDH1A1 (0.64) | MAOBNPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL8087605 | 0.81 | NQO1 (0.69) | MAOBNPC1NQO1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | EASTMAN CHEMICAL COMPANY | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | ABCC4, NCOA4, NR4A3 | MAOB 1213/4885NPC1 362/4885NQO1 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.