Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | NQO1 | P15559 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.59 |
| ▸ | TNKS | O95271 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5426832 | 0.92 | MAOB (0.75) | MAOBALDH1A1CYP2C9CYP2C19NQO1 | |
| SCHEMBL11479069 | 0.89 | MAOB (0.71) | MAOBALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL38652382 | 0.88 | MAOB (0.73) | MAOBALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7117556 | 0.87 | ALDH1A1 (0.67) | MAOBALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7122333 | 0.85 | NPC1 (0.68) | MAOBALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7117813 | 0.85 | ALDH1A1 (0.64) | MAOBALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28085675 | 0.85 | MAOB (0.65) | MAOBALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL11485562 | 0.83 | MAOB (1.00) | MAOBALDH1A1NQO1CA1CA2 | |
| SCHEMBL13819275 | 0.82 | ALDH1A1 (0.63) | MAOBALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11478035 | 0.81 | ERAP1 (0.74) | MAOBALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240060096-A1 | COMPOSITIONS AND METHODS FOR PRODUCING 1,8-DIHYDROXYNAPHTHALENE AND CYCLIC HYDROCARBONS FROM 1,8-DIHYDROXYNAPHTHALENE | TECH HOLDING LLC (US) | 2024-02-22 | — | — | US | disclosed |
| WO-2007115181-A9 | COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF | EASTMAN CHEM CO (US) | 2008-04-03 | — | — | WO | disclosed |
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | EASTMAN CHEMICAL COMPANY | 2007-11-01 | — | — | US | disclosed |
| WO-2007115181-A2 | COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF | EASTMAN CHEMICAL COMPANY (US) | 2007-10-11 | — | — | WO | disclosed |
| US-4230850-A | HYPOTENSIVE AGENTS, VASODILATION | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1980-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | ABCC4, NCOA4, NR4A3 | MAOB 1213/4885ALDH1A1 2000/4885CYP1A2 319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.