Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660021 | 0.94 | CTSS (0.39) | CTSSCTSKALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4661539 | 0.93 | MEN1 (0.42) | CTSSCTSKALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4660052 | 0.92 | CTSS (0.41) | CTSSCTSKALDH1A1MEN1KMT2A | |
| SCHEMBL4661384 | 0.91 | SLC6A4 (0.38) | CTSSCTSKKDM4EMEN1KMT2A | |
| SCHEMBL4660064 | 0.89 | KDM4E (0.38) | CTSSCTSKALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4661479 | 0.83 | ALDH1A1 (0.45) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL4661393 | 0.80 | KMT2A (0.47) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL4663676 | 0.79 | ALDH1A1 (0.43) | ALDH1A1ALOX5CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL4660164 | 0.79 | SMN1; SMN2 (0.41) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL4661361 | 0.78 | SMN1; SMN2 (0.41) | ALDH1A1MEN1KMT2AHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299105-A1 | 2-Cyanopropanoic Acid Amide and Ester Derivatives and Methods of Their Use | WYETH (US) | 2007-12-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299105-A1 | 2-Cyanopropanoic Acid Amide and Ester Derivatives and Methods of Their Use | HCAR2, PCCA, MCCC2 | CTSS 3385/4885CTSK 3140/4885ALDH1A1 1159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.