Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20631562 | 0.79 | HPGD (0.86) | ALDH1A1GAAHPGDL3MBTL1KDM4E | |
| SCHEMBL5371849 | 0.78 | MEN1 (0.56) | ALDH1A1MAPTGAAHSP90AA1MAPK1 | |
| SCHEMBL19479126 | 0.77 | ALDH1A1 (0.83) | ALDH1A1MAPTGAAMAPK1HPGD | |
| SCHEMBL27296588 | 0.75 | HPGD (0.64) | ALDH1A1MAPTGAAHPGDKDM4E | |
| SCHEMBL10053023 | 0.73 | HPGD (0.75) | ALDH1A1MAPTGAAHPGDL3MBTL1 | |
| SCHEMBL2534411 | 0.73 | HPGD (1.00) | ALDH1A1MAPTGAAHPGDL3MBTL1 | |
| SCHEMBL766272 | 0.72 | RBP4 (0.75) | ALDH1A1GAAHPGDKDM4EHTT | |
| SCHEMBL26487595 | 0.72 | GPR183 (0.73) | ALDH1A1MAPTGAAHSP90AA1MAPK1 | |
| SCHEMBL27508888 | 0.72 | ALDH1A1 (0.75) | ALDH1A1MAPTGAAMAPK1HPGD | |
| SCHEMBL2535536 | 0.72 | HPGD (0.96) | ALDH1A1MAPTGAAHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189739-B2 | Compounds and methods to treat cardiac failure and other disorders | SCIOS, INC. (US) | 2007-03-13 | — | — | US | disclosed |