Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.49 |
| ▸ | PHGDH | O43175 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5427258 | 0.78 | ALDH1A1 (0.57) | MEN1MAPTKMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL9585721 | 0.77 | POLB (0.81) | MAPTKMT2APOLBLMNAHSD17B10 | |
| SCHEMBL10722382 | 0.77 | POLB (0.81) | MAPTKMT2APOLBLMNAHSD17B10 | |
| SCHEMBL24158074 | 0.75 | LMNA (0.85) | MEN1MAPTKMT2ASMN1; SMN2POLB | |
| SCHEMBL2366564 | 0.74 | ALDH1A1 (0.63) | MEN1MAPTKMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL20524582 | 0.72 | ALDH1A1 (0.65) | MEN1MAPTKMT2ASMN1; SMN2POLB | |
| SCHEMBL9978124 | 0.72 | MEN1 (1.00) | MEN1MAPTKMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL22711992 | 0.71 | MAPT (0.66) | MEN1MAPTKMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL30323020 | 0.71 | MAPT (0.66) | MEN1MAPTKMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL6705171 | 0.71 | LMNA (0.88) | MEN1MAPTKMT2ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189739-B2 | Compounds and methods to treat cardiac failure and other disorders | SCIOS, INC. (US) | 2007-03-13 | — | — | US | disclosed |