Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 17/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 11/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5158658 | 0.92 | ITGA4 (0.41) | ITGA4ITGB1RORCLMNA | |
| SCHEMBL5428420 | 0.88 | ITGA4 (0.51) | ITGA4ITGB1RORCMEN1LMNA | |
| SCHEMBL5161591 | 0.87 | ITGA4 (0.39) | ITGA4ITGB1RORCLMNA | |
| SCHEMBL5158670 | 0.80 | ITGA4 (0.43) | ITGA4ITGB1RORCLMNAMAPT | |
| SCHEMBL5163265 | 0.80 | ITGB1 (0.52) | ITGA4ITGB1 | |
| SCHEMBL5423353 | 0.75 | ITGB1 (0.44) | ITGA4ITGB1 | |
| SCHEMBL5161598 | 0.75 | ITGA4 (0.40) | ITGA4ITGB1RORCLMNAMAPT | |
| SCHEMBL5160903 | 0.75 | ITGB1 (0.50) | ITGA4ITGB1 | |
| SCHEMBL14371671 | 0.73 | ITGA4 (0.54) | ITGA4ITGB1NPC1TP53PKM | |
| SCHEMBL5271980 | 0.73 | ITGA4 (0.55) | ITGA4ITGB1LMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | VCAM1, ITGB4, ITGA4 | ITGA4 3/4885ITGB1 9/4885RORC 486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.