Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5433592 | 0.85 | HDAC8 (0.53) | NR1H2NR1H3HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL5428822 | 0.84 | RAB9A (0.51) | MEN1KMT2ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL5431921 | 0.84 | NR1H2 (0.52) | ALDH1A1NR1H2NR1H3HDAC8HDAC6 | |
| SCHEMBL5433882 | 0.82 | FFAR1 (0.47) | MEN1KMT2AALDH1A1HSD17B2SMN1; SMN2 | |
| SCHEMBL3850447 | 0.78 | NPC1 (0.70) | MEN1KMT2AALDH1A1PLK1HDAC8 | |
| SCHEMBL30416225 | 0.78 | NPC1 (0.70) | MEN1KMT2AALDH1A1PLK1HDAC8 | |
| SCHEMBL13702375 | 0.78 | HDAC8 (0.68) | HDAC8HDAC6CYP3A4 | |
| SCHEMBL5423712 | 0.77 | HDAC8 (0.54) | ALDH1A1NR1H2NR1H3HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL30102161 | 0.77 | NPC1 (0.68) | MEN1KMT2AALDH1A1PLK1HDAC8 | |
| SCHEMBL5427874 | 0.76 | NR1H2 (0.48) | ALDH1A1NR1H2NR1H3HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070135497-A1 | Biphenyl derivative or its salt, and pesticide containing it as an active ingredient | ISHIHARA SANGYO KAISHA LTD. (JP) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135497-A1 | Biphenyl derivative or its salt, and pesticide containing it as an active ingredient | DDT, HCN1, HCN2 | MEN1 3354/4885KMT2A 135/4885ALDH1A1 3141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.