SCHEMBL5428903

SCHEMBL5428903

CCCCc1ccc(OS(=O)(=O)Cl)cc1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
HPGD P15428 2/20 0.45
ALDH1A1 P00352 1/20 0.44
HSD17B10 Q99714 1/20 0.44
FFAR1 O14842 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44
THRB P10828 2/20 0.44
STS P08842 4/20 0.44
CA1 P00915 2/20 0.42
CA9 Q16790 1/20 0.42
THRA P10827 1/20 0.42
RARB P10826 1/20 0.41
PLK1 P53350 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5269769 0.95 CA2 (0.53) CA2SMN1; SMN2ALDH1A1HSD17B10THRB
SCHEMBL5427923 0.93 CA2 (0.51) CA2SMN1; SMN2ALDH1A1HSD17B10THRB
SCHEMBL3655208 0.84 CA2 (0.53) CA2SMN1; SMN2HPGDALDH1A1HSD17B10
SCHEMBL14015390 0.82 CA2 (0.51) CA2SMN1; SMN2HPGDALDH1A1HSD17B10
SCHEMBL14063987 0.81 CA2 (0.45) CA2SMN1; SMN2HPGDALDH1A1STS
SCHEMBL276788 0.81 RARB (0.51) CA2SMN1; SMN2HPGDALDH1A1HSD17B10
SCHEMBL5265636 0.80 CA2 (0.56) CA2SMN1; SMN2ALDH1A1HSD17B10THRB
SCHEMBL1980097 0.79 CA2 (0.49) CA2SMN1; SMN2HPGDALDH1A1HSD17B10
SCHEMBL2829918 0.79 CA2 (0.49) CA2SMN1; SMN2HPGDALDH1A1HSD17B10
SCHEMBL10181185 0.79 CA2 (0.54) CA2SMN1; SMN2ALDH1A1HSD17B10THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070020309-A1 Safe and effective biofilm inhibitory compounds and health related uses thereof CUTLER, ELIOT 2007-01-25 US disclosed
US-7087661-B1 Safe and effective biofilm inhibitory compounds and health-related uses thereof CERNOFINA, LLC (US) 2006-08-08 US disclosed
EP-1115285-A1 SAFE AND EFFECTIVE BIOFILM INHIBITORY COMPOUNDS AND HEALTH-RELATED USES THEREOF Phycogen, Inc. (US) 2001-07-18 EP disclosed
EP-1115289-A2 ENVIRONMENTALLY BENIGN CROP PROTECTION AGENTS Phycogen, Inc. (US) 2001-07-18 EP disclosed
EP-1115284-A1 ANTIFOULING AGENTS Phycogen, Inc. (US) 2001-07-18 EP disclosed
WO-2000016624-A1 SAFE AND EFFECTIVE BIOFILM INHIBITORY COMPOUNDS AND HEALTH-RELATED USES THEREOF PHYCOGEN, INC. (US) 2000-03-30 WO disclosed
WO-2000016632-A2 ENVIRONMENTALLY BENIGN CROP PROTECTION AGENTS PHYCOGEN, INC. (US) 2000-03-30 WO disclosed
WO-2000016623-A1 ANTIFOULING AGENTS PHYCOGEN, INC. (US) 2000-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070020309-A1 Safe and effective biofilm inhibitory compounds and health related uses thereof FGB, TFPI, F3 CA2 2757/4885SMN1; SMN2 4792/4885HPGD 383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.