Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28541089 | 0.90 | KDM5A (0.54) | KDM5AL3MBTL1L3MBTL3GAATP53BP1 | |
| SCHEMBL27426 | 0.82 | KDM5A (0.40) | KDM5AKMT2A | |
| SCHEMBL4214094 | 0.80 | L3MBTL1 (0.38) | L3MBTL1L3MBTL3GAATP53BP1ACHE | |
| SCHEMBL16669802 | 0.78 | L3MBTL3 (0.40) | KDM5AL3MBTL1L3MBTL3MBTD1ALDH1A1 | |
| SCHEMBL21245631 | 0.78 | SMN1; SMN2 (0.41) | KDM5AL3MBTL1L3MBTL3TP53BP1ALOX15 | |
| SCHEMBL15797759 | 0.78 | ALDH1A1 (0.40) | KDM5AKDM4ECYP2C9CYP2C19KMT2A | |
| SCHEMBL30558157 | 0.78 | KDM5A (0.39) | KDM5AL3MBTL1L3MBTL3KDM4ECYP2C9 | |
| SCHEMBL8337639 | 0.77 | CHRM2 (0.44) | KDM5AL3MBTL1ACHEALOX15 | |
| SCHEMBL7190295 | 0.77 | ALDH1A1 (0.42) | KDM4ECYP2C9CYP2C19KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30612389 | 0.77 | KDM5A (0.38) | KDM5AL3MBTL1L3MBTL3KDM4ECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129361-A1 | LACTAM-CONTAINING DIAMINOALKYL, Beta-AMINOACIDS, Alpha-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | QIAO JENNIFER X | 2007-06-07 | — | — | US | claimed |
| US-20070129361-A1 | LACTAM-CONTAINING DIAMINOALKYL, Beta-AMINOACIDS, Alpha-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | QIAO JENNIFER X | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129361-A1 | LACTAM-CONTAINING DIAMINOALKYL, Beta-AMINOACIDS, Alpha-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | PEPD, XPNPEP1, METAP1 | KDM5A 3665/4885L3MBTL1 1475/4885L3MBTL3 3919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.