⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5178534 | 0.92 | — | — | |
| SCHEMBL10703408 | 0.90 | DNM1 (0.52) | — | |
| SCHEMBL3446836 | 0.82 | — | — | |
| SCHEMBL11511284 | 0.78 | ALDH1A1 (0.30) | — | |
| SCHEMBL3297434 | 0.74 | TSHR (0.41) | — | |
| SCHEMBL5586238 | 0.74 | — | — | |
| SCHEMBL270078 | 0.72 | — | — | |
| SCHEMBL95944 | 0.72 | — | — | |
| SCHEMBL9637201 | 0.72 | — | — | |
| SCHEMBL20276061 | 0.72 | LMNA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3290426-B1 | 2-CYANOETHYL-CONTAINING ORGANOXYSILANE COMPOUND, SILSESQUIOXANE, AND MAKING METHODS | SHINETSU CHEMICAL CO (JP) | 2021-11-17 | — | — | EP | disclosed |
| US-20070043089-A1 | METHOD OF INHIBITING ANGIOGENESIS | HAVIV FORTUNA | 2007-02-22 | — | — | US | disclosed |
| US-20070032527-A1 | METHOD OF INHIBITING ANGIOGENESIS | HAVIV FORTUNA | 2007-02-08 | — | — | US | disclosed |
| EP-1551404-A2 | METHOD OF INHIBITING ANGIOGENESIS | Abbott Laboratories (US) | 2005-07-13 | — | — | EP | disclosed |
| US-20040116479-A1 | Method of inhibiting angiogenesis | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |
| WO-2004032908-A9 | METHOD OF INHIBITING ANGIOGENESIS | ABBOTT LAB (US) | 2004-05-27 | — | — | WO | disclosed |
| WO-2004032908-A2 | METHOD OF INHIBITING ANGIOGENESIS | ABBOTT LABORATORIES (US) | 2004-04-22 | — | — | WO | disclosed |
| US-20040067985-A1 | Method of inhibiting angiogenesis | ABBOT LABORATORIES | 2004-04-08 | — | — | US | disclosed |
| US-RE30303-E | 1-AMINO-4-CYANO-1,3-BUTADIENE COMPOUNDS | EASTMAN KODAK COMPANY (US) | 1980-06-10 | — | — | US | disclosed |
| US-4045229-A | 1-AMINO-4-CYANO-1,3-BUTADIENE COMPOUNDS | EASTMAN KODAK COMPANY (US) | 1977-08-30 | — | — | US | disclosed |