Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13539052 | 0.83 | TSHR (0.46) | SMN1; SMN2TSHRNPC1RAB9AMAPT | |
| SCHEMBL2399420 | 0.72 | NPC1 (0.57) | SMN1; SMN2TSHRNPC1RAB9AMAPT | |
| SCHEMBL13541632 | 0.70 | TSHR (0.48) | SMN1; SMN2TSHRMAPTALDH1A1CA12 | |
| SCHEMBL520337 | 0.70 | TSHR (0.48) | SMN1; SMN2TSHRMAPTALDH1A1HPGD | |
| SCHEMBL11270905 | 0.70 | TSHR (0.48) | SMN1; SMN2TSHRMAPTALDH1A1HPGD | |
| SCHEMBL23069579 | 0.70 | TSHR (0.48) | SMN1; SMN2TSHRMAPTALDH1A1CA12 | |
| SCHEMBL28288962 | 0.70 | L3MBTL1 (0.50) | SMN1; SMN2TSHRNPC1RAB9AMAPT | |
| SCHEMBL1981603 | 0.69 | NOD2 (0.46) | SMN1; SMN2RAB9AMAPTALDH1A1HPGD | |
| SCHEMBL5257098 | 0.68 | TSHR (0.46) | SMN1; SMN2TSHRRAB9AMAPTALDH1A1 | |
| SCHEMBL17574712 | 0.68 | TSHR (0.46) | SMN1; SMN2TSHRMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070015746-A1 | Azepine derivaties as pharmaceutical agents | X-CEPTOR THERAPEUTICS INC. (US) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015746-A1 | Azepine derivaties as pharmaceutical agents | HTR5A, TACR2, TACR1 | SMN1; SMN2 2388/4885TSHR 138/4885NPC1 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.