Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5424173 | 0.89 | HDAC8 (0.50) | HDAC8HDAC6MAP4K4NR1H2NR1H3 | |
| SCHEMBL5427874 | 0.85 | NR1H2 (0.48) | HDAC8HDAC6MAP4K4NR1H2NR1H3 | |
| SCHEMBL5423712 | 0.84 | HDAC8 (0.54) | HDAC8HDAC6MAP4K4NR1H2NR1H3 | |
| SCHEMBL5423820 | 0.84 | HDAC8 (0.49) | HDAC8HDAC6MAP4K4NR1H2NR1H3 | |
| SCHEMBL5427907 | 0.81 | RAF1 (0.48) | HDAC8HDAC6NR1H2NR1H3CDK8 | |
| SCHEMBL5428135 | 0.80 | MAPT (0.44) | HDAC8HDAC6NR1H2NR1H3MEN1 | |
| SCHEMBL5431921 | 0.79 | NR1H2 (0.52) | HDAC8HDAC6NR1H2NR1H3CDK8 | |
| SCHEMBL13702375 | 0.75 | HDAC8 (0.68) | HDAC8HDAC6MAP4K4CDK8NR4A2 | |
| SCHEMBL5433592 | 0.74 | HDAC8 (0.53) | HDAC8HDAC6MAP4K4NR1H2NR1H3 | |
| SCHEMBL879253 | 0.73 | ALDH1A1 (0.53) | HDAC8HDAC6HDAC2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070135497-A1 | Biphenyl derivative or its salt, and pesticide containing it as an active ingredient | ISHIHARA SANGYO KAISHA LTD. (JP) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135497-A1 | Biphenyl derivative or its salt, and pesticide containing it as an active ingredient | DDT, HCN1, HCN2 | HDAC8 967/4885HDAC6 1100/4885MAP4K4 4409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.