Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL1903839 | 1.00 | TSHR (0.31) | — | |
| Guanidine SCHEMBL29044101 | 1.00 | TSHR (0.31) | — | |
| Guanidine SCHEMBL27473938 | 0.96 | — | — | |
| Guanidine SCHEMBL7755519 | 0.96 | — | — | |
| Guanidine SCHEMBL31206959 | 0.96 | — | — | |
| Guanidine SCHEMBL6529495 | 0.96 | — | — | |
| Guanidine SCHEMBL6851202 | 0.96 | — | — | |
| Guanidine SCHEMBL27492536 | 0.92 | — | — | |
| Guanidine SCHEMBL28453453 | 0.92 | — | — | |
| Guanidine SCHEMBL28312113 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 24299 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122081048-A | Portable ultra-fast PCR detection system and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122071736-A | Free DNA extraction kit, extraction method and application | 武汉华大智造科技有限公司 | 2026-05-22 | — | — | CN | claimed |
| CN-120118976-B | Virus stock solution and preparation method thereof | 湖北工业大学 | 2026-05-22 | — | — | CN | claimed |
| CN-122071698-A | Extraction reagent, kit and extraction method for small RNA in circulating body fluid and library construction method for small RNA in circulating body fluid | 南京大学 | 2026-05-22 | — | — | CN | claimed |
| CN-122060720-A | Plasmid extraction method and kit based on efficient pyrolysis and rapid column balance | 吉诺(南通)生物技术有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122038537-A | Bacterial RNA normal-temperature preservation solution for sputum sample of tuberculosis patient | 北京市疾病预防控制中心 | 2026-05-15 | — | — | CN | claimed |
| WO-2026098386-A1 | AGROCHEMICAL ADHESION SYNERGIST BASED ON PLANT-DERIVED PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 陕西师范大学 | 2026-05-15 | — | — | WO | claimed |
| CN-122012491-A | Method for extracting giardia and cryptosporidium nucleic acid and application thereof | 江苏奇天基因生物科技有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122012671-A | Tongue swab sample preservation solution and application thereof | 圣湘生物科技股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| EP-4731795-A2 | SELECTIVE MULTIPLEXED ELECTROCHEMICAL PLATFORM FOR DETECTION OF HIV INFECTION | University of Maryland, Baltimore (US) | 2026-04-29 | — | — | EP | claimed |
| EP-0487646-A1 | METHODS AND COMPOSITIONS FOR ISOLATION OF NUCLEIC ACIDS FROM EUKARYOTIC AND PROKARYOTIC SOURCES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1992-06-03 | — | — | EP | claimed |
| WO-1991002740-A1 | METHODS AND COMPOSITIONS FOR ISOLATION OF NUCLEIC ACIDS FROM EUKARYOTIC AND PROKARYOTIC SOURCES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1991-03-07 | — | — | WO | claimed |
| EP-0382720-A4 | DIAGNOSING OBESITY CAUSED BY A GENETIC ABNORMALITY AND METHOD OF THERAPEUTICALLY TREATING GENETICALLY CAUSED OBESITY | — | 1991-01-02 | — | — | EP | claimed |
| EP-0382720-A1 | DIAGNOSING OBESITY CAUSED BY A GENETIC ABNORMALITY AND METHOD OF THERAPEUTICALLY TREATING GENETICALLY CAUSED OBESITY. | BETH ISRAEL HOSPITAL (US) | 1990-08-22 | — | — | EP | claimed |
| EP-0370032-A1 | PROCESS FOR TESTING A BIOLOGICAL FLUID FOR CELLULAR ONCOGEN DNA OR FRAGMENTS THEREOF | BALAZS, Viktor, Dr. Dr. med. (DE) | 1990-05-30 | — | — | EP | claimed |
| EP-0360822-A1 | PROCESS FOR INVESTIGATING AN ACELLULAR BIOLOGICAL FLUID FOR CELLULAR ONCOGENIC TRANSCRIPTS OR FRAGMENTS THEREOF | BALAZS, Viktor, Dr. Dr. med. (DE) | 1990-04-04 | — | — | EP | claimed |
| EP-0310913-A2 | DNA isolation procedure | BIOTECHNICA DIAGNOSTICS INC (US) | 1989-04-12 | — | — | EP | claimed |
| WO-1989000206-A1 | PROCESS FOR TESTING A BIOLOGICAL FLUID FOR CELLULAR ONCOGEN DNA OR FRAGMENTS THEREOF | BALAZS VIKTOR (DE) | 1989-01-12 | — | — | WO | claimed |
| WO-1988009385-A1 | PROCESS FOR INVESTIGATING AN ACELLULAR BIOLOGICAL FLUID FOR CELLULAR ONCOGENIC TRANSCRIPTS OR FRAGMENTS THEREOF | BALAZS VIKTOR (DE) | 1988-12-01 | — | — | WO | claimed |
| WO-1988007681-A1 | DIAGNOSING OBESITY CAUSED BY A GENETIC ABNORMALITY AND METHOD OF THERAPEUTICALLY TREATING GENETICALLY CAUSED OBESITY | THE BETH ISRAEL HOSPITAL ASSOCIATION (US) | 1988-10-06 | — | — | WO | claimed |