Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.65 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.65 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.65 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.65 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | POLG | P54098 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14581404 | 1.00 | ALB (0.65) | ALBMAPTLMNACACNA1FCACNA1D | |
| SCHEMBL31289523 | 1.00 | ALB (0.65) | ALBMAPTLMNACACNA1FCACNA1D | |
| SCHEMBL5437126 | 1.00 | ALB (0.65) | ALBMAPTLMNACACNA1FCACNA1D | |
| SCHEMBL15253100 | 0.90 | ALB (0.66) | ALBMAPTLMNACACNA1FCACNA1D | |
| SCHEMBL14420735 | 0.89 | ALB (0.62) | ALBMAPTLMNACACNA1FCACNA1D | |
| SCHEMBL29399701 | 0.89 | ALB (0.53) | ALBMAPTLMNACACNA1FCACNA1D | |
| SCHEMBL14416476 | 0.88 | ALB (0.64) | ALBMAPTLMNACACNA1FCACNA1D | |
| SCHEMBL16127112 | 0.87 | ALB (0.69) | ALBMAPTLMNACACNA1FCACNA1D | |
| SCHEMBL15014703 | 0.87 | ALB (0.69) | ALBMAPTLMNACACNA1FCACNA1D | |
| SCHEMBL15045866 | 0.87 | ALB (0.69) | ALBMAPTLMNACACNA1FCACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037975-A1 | Substituted-1,3-oxathiolanes and substituted-1, 3-dioxolanes with antiviral properties | BELLEAU BERNARD | 2007-02-15 | — | — | US | claimed |
| EP-0515144-B1 | 1,3-Oxathiolanes useful in the treatment of hepatitis | SHIRE BIOCHEM INC (CA) | 2006-06-14 | — | — | EP | claimed |
| US-20040254201-A1 | Substituted-1,3-oxathiolanes and substituted-1,3-dioxolanes with antiviral properties | BELLEAU BERNARD (CA) | 2004-12-16 | — | — | US | claimed |
| US-20030087918-A1 | Synthesis of substituted 1,3-dioxolanes and substituted 1,3-oxathiolanes with antiviral properties | BIOCHEM PHARMA INC. (CA) | 2003-05-08 | — | — | US | claimed |
| EP-0711771-A2 | Substituted-1,3-oxathiolanes with antiviral properties | BIOCHEM PHARMA INC. (CA) | 1996-05-15 | — | — | EP | claimed |
| EP-0515144-A1 | 1,3-Oxathiolanes useful in the treatment of hepatitis | BIOCHEM PHARMA INC. (CA) | 1992-11-25 | — | — | EP | claimed |
| EP-0382526-A2 | Substituted -1,3-oxathiolanes with antiviral properties | BIOCHEM PHARMA INC (CA) | 1990-08-16 | — | — | EP | claimed |
| US-20070037977-A1 | Substituted-1, 3-oxathiolanes and substituted-1, 3-dioxolanes with antiviral properties | BELLEAU BERNARD | 2007-02-15 | — | — | US | disclosed |
| US-20070037975-A1 | Substituted-1,3-oxathiolanes and substituted-1, 3-dioxolanes with antiviral properties | BELLEAU BERNARD | 2007-02-15 | — | — | US | disclosed |
| US-7122693-B2 | Acetaldehyde acetal compounds, their synthesis, and uses thereof | SHIRE BIOCHEM INC. (CA) | 2006-10-17 | — | — | US | disclosed |
| US-7119202-B1 | Substituted-1,3-oxathiolanes and substituted-1,3-dioxolanes with antiviral properties | GLAXO WELLCOME INC. (US) | 2006-10-10 | — | — | US | disclosed |
| EP-0515144-B1 | 1,3-Oxathiolanes useful in the treatment of hepatitis | SHIRE BIOCHEM INC (CA) | 2006-06-14 | — | — | EP | disclosed |
| US-6903224-B2 | Substituted 1,3-oxathiolanes | BIOCHEM PHARMA INC. (CA) | 2005-06-07 | — | — | US | disclosed |
| US-20040254201-A1 | Substituted-1,3-oxathiolanes and substituted-1,3-dioxolanes with antiviral properties | BELLEAU BERNARD (CA) | 2004-12-16 | — | — | US | disclosed |
| EP-0711771-B1 | Substituted-1,3-oxathiolanes with antiviral properties | SHIRE BIOCHEM INC (CA) | 2003-11-12 | — | — | EP | disclosed |
| US-20030087918-A1 | Synthesis of substituted 1,3-dioxolanes and substituted 1,3-oxathiolanes with antiviral properties | BIOCHEM PHARMA INC. (CA) | 2003-05-08 | — | — | US | disclosed |
| US-6350753-B1 | 2-ACETOXYMETHYL-4-(THYMIN-1'-YL)-1,3,-DIOXOLANE; 2-BENZOYLOXYMETHYL-4-(CYTOSIN-1'-YL)-1,3-DIOXOLANE; ANTIVIRAL AGENTS, PARTICULARY FOR THE TREATMENT OF THE HIV INFECTIONS IN MAMMALS, ESPECIALLY HUMANS | BIOCHEM PHARMA INC. (CA) | 2002-02-26 | — | — | US | disclosed |
| EP-0711771-A2 | Substituted-1,3-oxathiolanes with antiviral properties | BIOCHEM PHARMA INC. (CA) | 1996-05-15 | — | — | EP | disclosed |
| EP-0515144-A1 | 1,3-Oxathiolanes useful in the treatment of hepatitis | BIOCHEM PHARMA INC. (CA) | 1992-11-25 | — | — | EP | disclosed |
| EP-0382526-A2 | Substituted -1,3-oxathiolanes with antiviral properties | BIOCHEM PHARMA INC (CA) | 1990-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037977-A1 | Substituted-1, 3-oxathiolanes and substituted-1, 3-dioxolanes with antiviral properties | IFNAR1, MAVS, IFNG | ALB 1678/4885MAPT 4740/4885LMNA 4245/4885 |
| US-20070037975-A1 | Substituted-1,3-oxathiolanes and substituted-1, 3-dioxolanes with antiviral properties | IFNAR1, MAVS, IFNG | ALB 1877/4885MAPT 4789/4885LMNA 4227/4885 |
| US-20030087918-A1 | Synthesis of substituted 1,3-dioxolanes and substituted 1,3-oxathiolanes with antiviral properties | IFNAR1, ZC3HAV1, NUDT1 | ALB 2629/4885MAPT 4729/4885LMNA 3528/4885 |
| US-20040254201-A1 | Substituted-1,3-oxathiolanes and substituted-1,3-dioxolanes with antiviral properties | IFNAR1, ZC3HAV1, MAVS | ALB 2403/4885MAPT 4712/4885LMNA 3612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.