Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310997 | 0.85 | LTA4H (0.67) | LTA4HFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL3040049 | 0.77 | LTA4H (0.65) | LTA4HFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL3038141 | 0.77 | LTA4H (0.65) | LTA4HFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL5471639 | 0.76 | LTA4H (0.81) | LTA4HALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5314382 | 0.75 | LTA4H (0.82) | LTA4HFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL3026400 | 0.75 | CHKA (0.65) | LTA4HFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL5310987 | 0.72 | LTA4H (0.83) | LTA4HFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL22042582 | 0.71 | RAB9A (0.57) | ALDH1A1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL1256116 | 0.71 | L3MBTL1 (0.57) | ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL6159348 | 0.69 | HCRTR1 (0.53) | LTA4HFAAHALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079003-A2 | AMIDE INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-07-12 | — | — | WO | disclosed |