Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11929887 | 0.83 | ADORA3 (0.53) | TLR7HPGDSTING1PDE3BPDE3A | |
| SCHEMBL4323450 | 0.83 | ADORA3 (0.53) | TLR7HPGDSTING1PDE3BPDE3A | |
| SCHEMBL16695880 | 0.83 | ADORA3 (0.53) | TLR7HPGDSTING1PDE3BPDE3A | |
| SCHEMBL18759056 | 0.83 | ADORA3 (0.53) | TLR7HPGDSTING1PDE3BPDE3A | |
| SCHEMBL13833321 | 0.83 | ADORA3 (0.53) | TLR7HPGDSTING1PDE3BPDE3A | |
| SCHEMBL9200583 | 0.83 | ADORA3 (0.53) | TLR7HPGDSTING1PDE3BPDE3A | |
| SCHEMBL98907 | 0.83 | ADORA3 (0.53) | TLR7HPGDSTING1PDE3BPDE3A | |
| SCHEMBL98906 | 0.83 | ADORA3 (0.53) | TLR7HPGDSTING1PDE3BPDE3A | |
| SCHEMBL12031117 | 0.83 | ADORA3 (0.53) | TLR7HPGDSTING1PDE3BPDE3A | |
| Deoxyguanosine SCHEMBL14604160 | 0.80 | ADRB1 (0.60) | ADRB1DNMT1LMNAPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110676-B2 | Prodrugs activated by RNA-dependent DNA-polymerases | PROTERA S.R.L. (IT) | 2012-02-07 | — | — | US | claimed |