Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.39 |
| ▸ | F2 | P00734 | 7/20 | 0.39 |
| ▸ | CTRC | Q99895 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 6/20 | 0.35 |
| ▸ | NOS3 | P29474 | 5/20 | 0.35 |
| ▸ | NOS2 | P35228 | 5/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428209 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2CA1CA9 | |
| SCHEMBL14563330 | 0.76 | NOS1 (0.35) | PRSS1F2CTRCNOS1NOS3 | |
| SCHEMBL18965610 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2CA1CA9 | |
| SCHEMBL16057985 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2PRSS1F2CTRCNOS1 | |
| SCHEMBL14026635 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2PRSS1F2CTRCCA1 | |
| SCHEMBL21475402 | 0.73 | ICAM1 (0.33) | SMN1; SMN2 | |
| SCHEMBL15527998 | 0.73 | CYP2D6 (0.34) | PRSS1F2CTRCCYP2D6CHRM2 | |
| SCHEMBL21475332 | 0.73 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL5529318 | 0.71 | PRSS1 (0.44) | PRSS1F2CTRCCYP2D6 | |
| SCHEMBL17105744 | 0.71 | SMN1; SMN2 (0.32) | SMN1; SMN2PRSS1F2CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6462015-B1 | OCTAHYHYDRO-3- AND 4-METHYL-2H-1-BENZOPYRAN-2-ONES INTENSIFIERS; LOW COST; SYNTHESIZED FROM CYCLOHEXANONE OR CYCLOPENTANONE BY AMINATION, ALKYLESTERIFICATION, DEAMINATION AND CYCLIZATION | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-10-08 | — | — | US | claimed |
| CN-101602755-B | Method for synthesizing 9, 11-dimethyl-2-oxaspiro [5, 5]-undecanoic-3-one | SHANGHAI INST TECHNOLOGY | 2011-06-29 | — | — | CN | disclosed |
| CN-101774998-A | 3-methyl-octahydro-cycloheptatriene oxapicene-2-ketone and preparation method thereof | SHANGHAI RES INST OF FRAGRANCE | 2010-07-14 | — | — | CN | disclosed |
| CN-101602755-A | 9, the preparation method of 11-dimethyl-2-oxaspiro [5,5]-undecane-3-ketone | SHANGHAI INST TECHNOLOGY (CN) | 2009-12-16 | — | — | CN | disclosed |
| US-20070054837-A1 | Bicyclic lactones, perfumery uses thereof, processes for preparing same and intermediates therefor | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-03-08 | — | — | US | disclosed |
| US-20070054837-A1 | Bicyclic lactones, perfumery uses thereof, processes for preparing same and intermediates therefor | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-03-08 | — | — | US | disclosed |
| US-20070054837-A1 | Bicyclic lactones, perfumery uses thereof, processes for preparing same and intermediates therefor | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-03-08 | — | — | US | disclosed |
| US-7169747-B2 | Bicyclic lactones, perfumery uses thereof, processes for preparing same and intermediates therefor | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2007-01-30 | — | — | US | disclosed |
| US-7169747-B2 | Bicyclic lactones, perfumery uses thereof, processes for preparing same and intermediates therefor | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2007-01-30 | — | — | US | disclosed |
| US-6835699-B2 | Fused ring lactones and spiro lactones; used for augmenting or enhancing the aroma of perfume compositions and articles | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2004-12-28 | — | — | US | disclosed |
| US-20030224966-A1 | Bicycle lactones, perfumery uses thereof, processes for preparing same and intermediates therefor | WEISS RICHARD A (US) | 2003-12-04 | — | — | US | disclosed |
| US-6608010-B2 | Mixing cyclic esters with detergents, fabric softeners or thermoplastic resins as odor intensifiers; organoleptics | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2003-08-19 | — | — | US | disclosed |
| US-20030096729-A1 | Bicyclic lactones, perfumery uses thereof, processes for preparing same and intermediates therefor | WEISS RICHARD A (US) | 2003-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030224966-A1 | Bicycle lactones, perfumery uses thereof, processes for preparing same and intermediates therefor | NOTUM, CASP8, CBR1 | SMN1; SMN2 4156/4885PRSS1 2046/4885F2 63/4885 |
| US-20030096729-A1 | Bicyclic lactones, perfumery uses thereof, processes for preparing same and intermediates therefor | NOTUM, CASP8, CBR1 | SMN1; SMN2 4096/4885PRSS1 1872/4885F2 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.