SCHEMBL5529318

SCHEMBL5529318

CC1C(=O)OC2CCCCC21

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 10/20 0.44
F2 P00734 9/20 0.44
CTRC Q99895 2/20 0.44
TAS2R46 P59540 6/20 0.42
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP2D6 P10635 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12836373 0.96 PRSS1 (0.49) PRSS1F2CTRCTAS2R46MEN1
SCHEMBL7886105 0.76 PRSS1 (0.46) PRSS1F2CTRC
SCHEMBL6672676 0.76 PRSS1 (0.46) PRSS1F2CTRC
SCHEMBL6668341 0.76 PRSS1 (0.46) PRSS1F2CTRC
SCHEMBL6668345 0.76 PRSS1 (0.46) PRSS1F2CTRC
SCHEMBL24026904 0.75 TAS2R46 (0.47) TAS2R46MEN1KMT2A
SCHEMBL4097512 0.75 TAS2R46 (0.47) TAS2R46MEN1KMT2A
SCHEMBL8628231 0.75 TAS2R46 (0.47) TAS2R46MEN1KMT2A
SCHEMBL21316644 0.75 TAS2R46 (0.47) TAS2R46MEN1KMT2A
SCHEMBL9244208 0.75 TAS2R46 (0.47) TAS2R46MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0167265-B1 Method of repelling insects COULSTON INT CORP (US) 1995-12-20 EP claimed
US-10392357-B2 Glucagon-like peptide 1 modulator and uses thereof ACAEMIA SINICA (TW) 2019-08-27 US disclosed
US-20180179172-A1 NOVEL GLUCAGON-LIKE PEPTIDE 1 MODULATOR AND USES THEREOF ACADEMIA SINICA (TW) 2018-06-28 US disclosed
US-8173353-B2 Sulfonium compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-08 US disclosed
US-8173353-B2 Sulfonium compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-08 US disclosed
US-20100248135-A1 SULFONIUM COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-30 US disclosed
US-20100248135-A1 SULFONIUM COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-30 US disclosed
US-7687219-B2 Positive resist composition and pattern formation method using the positive resist composition FUJIFILM CORPORATION (JP) 2010-03-30 US disclosed
US-7687219-B2 Positive resist composition and pattern formation method using the positive resist composition FUJIFILM CORPORATION (JP) 2010-03-30 US disclosed
US-7632623-B2 Positive resist composition and pattern formation method using the positive resist composition FUJIFILM CORPORATION (JP) 2009-12-15 US disclosed
EP-1835340-A1 Positive resist composition and pattern formation method using the positive resist composition FUJIFILM Corporation (JP) 2007-09-19 EP disclosed
EP-1835343-A1 Positive resist composition and pattern formation method using the positive resist composition FUJIFILM Corporation (JP) 2007-09-19 EP disclosed
US-20070105045-A1 Positive resist composition and pattern formation method using the positive resist composition FUJIFILM CORPORATION 2007-05-10 US disclosed
US-20070105045-A1 Positive resist composition and pattern formation method using the positive resist composition FUJIFILM CORPORATION 2007-05-10 US disclosed
EP-0167265-B1 Method of repelling insects COULSTON INT CORP (US) 1995-12-20 EP disclosed
EP-0666027-A1 Method of repelling insects COULSTON INTERNATIONAL CORPORATION (US) 1995-08-09 EP disclosed
EP-0167266-B1 INSECT REPELLENT COMPOSITION AND METHOD OF REPELLING INSECTS ANGUS CHEMICAL COMPANY (US) 1989-08-02 EP disclosed
US-4663346-A Insect repellent ANGUS CHEMICAL COMPANY (US) 1987-05-05 US disclosed
EP-0167266-A1 Insect repellent composition and method of repelling insects ANGUS CHEMICAL COMPANY (US) 1986-01-08 EP disclosed
EP-0167265-A1 Method of repelling insects COULSTON INTERNATIONAL CORPORATION (US) 1986-01-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392357-B2 Glucagon-like peptide 1 modulator and uses thereof GLP1R, IAPP, GIPR PRSS1 1377/4885F2 4313/4885CTRC 2260/4885
US-20100248135-A1 SULFONIUM COMPOUND PFAS, F12, AFF1 PRSS1 944/4885F2 261/4885CTRC 2532/4885
US-20180179172-A1 NOVEL GLUCAGON-LIKE PEPTIDE 1 MODULATOR AND USES THEREOF GLP1R, IAPP, GIPR PRSS1 1197/4885F2 4483/4885CTRC 2031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.