Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.54 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5441501 | 0.95 | FABP4 (0.48) | FABP4PRKCAMMP12KMO | |
| SCHEMBL5435711 | 0.93 | FABP4 (0.49) | FABP4PRKCAMMP12TP53PPARG | |
| SCHEMBL5440965 | 0.91 | FABP4 (0.46) | FABP4PRKCAMMP12MAPK8KMO | |
| SCHEMBL5443057 | 0.91 | FABP4 (0.45) | FABP4PRKCAMMP12LMNATP53 | |
| SCHEMBL5431063 | 0.91 | FABP4 (0.44) | FABP4PRKCAMMP12MAPK8KMO | |
| SCHEMBL5440988 | 0.90 | FABP4 (0.47) | FABP4PRKCAMMP12TP53CNR2 | |
| SCHEMBL5437196 | 0.90 | FABP4 (0.46) | FABP4PRKCAMMP12MAPK8LMNA | |
| Hydrochloric Acid SCHEMBL5444964 | 0.90 | CNR2 (0.45) | FABP4PRKCAMMP12CNR2 | |
| SCHEMBL5439956 | 0.89 | FABP4 (0.43) | FABP4PRKCAMMP12PDE1CHDAC1 | |
| SCHEMBL5444413 | 0.86 | PRKCA (0.46) | FABP4PRKCAMMP12KMOSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072911-A1 | Indoles and azaindoles as antiviral agents | AVOLIO SALVATORE | 2007-03-29 | — | — | US | claimed |
| CN-1863528-A | Indoles and azaindoles as antiviral agents | ANGELETTI P IST RICHERCHE BIO (IT) | 2006-11-15 | — | — | CN | claimed |
| EP-1673081-A1 | INDOLES AND AZAINDOLES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2006-06-28 | — | — | EP | claimed |
| WO-2005034941-A1 | INDOLES AND AZAINDOLES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2005-04-21 | — | — | WO | claimed |
| US-20070072911-A1 | Indoles and azaindoles as antiviral agents | AVOLIO SALVATORE | 2007-03-29 | — | — | US | disclosed |
| EP-1673081-A1 | INDOLES AND AZAINDOLES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005034941-A1 | INDOLES AND AZAINDOLES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2005-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072911-A1 | Indoles and azaindoles as antiviral agents | IDO1, IDO2, NAT1 | FABP4 4683/4885PRKCA 4799/4885MMP12 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.