Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5432018 | 0.90 | FABP4 (0.54) | FABP4PRKCAMMP12MAPK8PPARG | |
| SCHEMBL5435711 | 0.89 | FABP4 (0.49) | FABP4PRKCAMMP12PPARG | |
| SCHEMBL5441501 | 0.85 | FABP4 (0.48) | FABP4PRKCAMMP12 | |
| SCHEMBL5443057 | 0.83 | FABP4 (0.45) | FABP4PRKCAMMP12LMNA | |
| SCHEMBL5431063 | 0.83 | FABP4 (0.44) | FABP4PRKCAMMP12MAPK8PPARG | |
| SCHEMBL5440988 | 0.83 | FABP4 (0.47) | FABP4PRKCAMMP12 | |
| SCHEMBL5440965 | 0.81 | FABP4 (0.46) | FABP4PRKCAMMP12MAPK8PPARG | |
| SCHEMBL5783672 | 0.81 | PRKCA (0.46) | FABP4PRKCAMMP12PTGESSCN9A | |
| SCHEMBL5434803 | 0.80 | PRKCA (0.44) | FABP4PRKCAMMP12MAPK8PPARG | |
| Hydrochloric Acid SCHEMBL5444964 | 0.80 | CNR2 (0.45) | FABP4PRKCAMMP12TBXA2RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072911-A1 | Indoles and azaindoles as antiviral agents | AVOLIO SALVATORE | 2007-03-29 | — | — | US | claimed |
| CN-1863528-A | Indoles and azaindoles as antiviral agents | ANGELETTI P IST RICHERCHE BIO (IT) | 2006-11-15 | — | — | CN | claimed |
| EP-1673081-A1 | INDOLES AND AZAINDOLES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2006-06-28 | — | — | EP | claimed |
| WO-2005034941-A1 | INDOLES AND AZAINDOLES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2005-04-21 | — | — | WO | claimed |
| US-20070072911-A1 | Indoles and azaindoles as antiviral agents | AVOLIO SALVATORE | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072911-A1 | Indoles and azaindoles as antiviral agents | IDO1, IDO2, NAT1 | FABP4 4683/4885PRKCA 4799/4885MMP12 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.