Salclobuzic Acid

Salclobuzic Acid

SCHEMBL543359

O=C(O)CCCNC(=O)c1ccc(Cl)cc1O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 1/20 0.57
CDK1 P06493 1/20 0.57
CA1 P00915 5/20 0.53
CA2 P00918 5/20 0.53
CA12 O43570 3/20 0.53
CA3 P07451 3/20 0.53
CA4 P22748 3/20 0.53
CA6 P23280 3/20 0.53
CA7 P43166 3/20 0.53
CA9 Q16790 3/20 0.53
CA13 Q8N1Q1 3/20 0.53
CA14 Q9ULX7 3/20 0.53
CA5B Q9Y2D0 3/20 0.53
CA5A P35218 2/20 0.53
TDP1 Q9NUW8 2/20 0.51
POLB P06746 1/20 0.49
THRB P10828 1/20 0.49
RECQL P46063 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
KLKB1 P03952 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salclobuzic Acid SCHEMBL15484586 0.99 FABP4 (0.56) FABP4CDK1CA1CA2CA12
Salclobuzic Acid SCHEMBL28863372 0.99 FABP4 (0.56) FABP4CDK1CA1CA2CA12
Salclobuzic Acid SCHEMBL30966700 0.99 FABP4 (0.56) FABP4CDK1CA1CA2CA12
Salclobuzic Acid SCHEMBL1070672 0.97 FABP4 (0.55) FABP4CDK1CA1CA2CA12
SCHEMBL4390458 0.96 CDK1 (0.56) FABP4CDK1CA1CA2CA12
SCHEMBL4624092 0.94 MAPK1 (0.55) FABP4CDK1CA1CA2CA12
SCHEMBL5654581 0.94 MAPK1 (0.55) FABP4CDK1CA1CA2CA12
SCHEMBL13593295 0.94 MAPK1 (0.55) FABP4CDK1CA1CA2CA12
SCHEMBL26702537 0.89 CDK1 (0.55) FABP4CDK1CA1CA2CA12
SCHEMBL2330956 0.88 CDK1 (0.74) FABP4CDK1CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260071218-A1 Oral Delivery of Antisense Conjugates Targeting PCSK9 CIVI BIOPHARMA INC (US) 2026-03-12 US claimed
EP-4651897-A1 PERMEATION ENHANCERS FOR GASTROINTESTINAL SYNTHETIC EPITHELIAL LININGS Syntis Bio, Inc. (US) 2025-11-26 EP claimed
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO claimed
CN-118873509-A Oral pharmaceutical composition 西藏海思科制药有限公司 2024-11-01 CN claimed
US-20240261411-A1 PERMEATION ENHANCERS FOR GASTROINTESTINAL SYNTHETIC EPITHELIAL LININGS SYNTIS BIO, INC. 2024-08-08 US claimed
WO-2024155958-A1 PERMEATION ENHANCERS FOR GASTROINTESTINAL SYNTHETIC EPITHELIAL LININGS SYNTIS BIO, INC. (US) 2024-07-25 WO claimed
US-20240067965-A1 ORAL DELIVERY OF ANTISENSE CONJUGATES TARGETING PCSK9 CIVI BIOPHARMA INC (US) 2024-02-29 US claimed
EP-4299052-A1 SOLID COMPOSITIONS COMPRISING A PEPTIDE OR A PROTEIN AND A PERMEATION ENHANCER Adocia (FR) 2024-01-03 EP claimed
EP-4259799-A1 ORAL DELIVERY OF ANTISENSE CONJUGATES TARGETING PCSK9 Civi Biopharma, Inc. (US) 2023-10-18 EP claimed
CN-116897206-A Oral delivery of PCSK 9-targeting antisense conjugates 四纬生物制药股份有限公司 2023-10-17 CN claimed
WO-2006124047-A9 PHARMACEUTICAL FORMULATIONS CONTAINING MICROPARTICLES OR NANOPARTICLES OF A DELIVERY AGENT EMISPHERE TECH INC (US) 2007-06-21 WO claimed
CN-1964724-A Solid dosage forms of wetted heparin EMISPHERE TECH INC (US) 2007-05-16 CN claimed
EP-1781257-A2 PHARMACEUTICAL FORMULATIONS CONTAINING MICROPARTICLES OR NANOPARTICLES OF A DELIVERY AGENT Emisphere Technologies, Inc. (US) 2007-05-09 EP claimed
US-7208178-B2 Polymorphs of sodium 4-[(4-chloro-2-hydroxybenzoyl) amino] butanoate EMISPHERE TECHNOLOGIES, INC. (US) 2007-04-24 US claimed
WO-2006124047-A2 PHARMACEUTICAL FORMULATIONS CONTAINING MICROPARTICLES OR NANOPARTICLES OF A DELIVERY AGENT EMISPHERE TECHNOLOGIES, INC. (US) 2006-11-23 WO claimed
EP-1469827-A4 POLYMORPHS OF SODIUM 4- (4-CHLORO-2-HYDROXYBENZOYL)AMINO BUTANOATE EMISPHERE TECH INC (US) 2006-08-16 EP claimed
WO-2006072070-A2 PHARMACEUTICAL FORMULATIONS OF GALLIUM SALTS EMISPHERE TECHNOLOGIES, INC. (US) 2006-07-06 WO claimed
US-20050250852-A1 Polymorphs of sodium 4-[(4-chloro-2-hydroxybenzoyl) amino] butanoate EMISPHERE TECHNOLOGIES, INC. (US) 2005-11-10 US claimed
EP-1469827-A2 POLYMORPHS OF SODIUM 4- (4-CHLORO-2-HYDROXYBENZOYL)AMINO BUTANOATE Emisphere Technologies, Inc. (US) 2004-10-27 EP claimed
WO-2003057650-A2 POLYMORPHS OF SODIUM 4-[(4-CHLORO-2-HYDROXYBENZOYL)AMINO]BUTANOATE EMISPHERE TECHNOLOGIES, INC. (US) 2003-07-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240261411-A1 PERMEATION ENHANCERS FOR GASTROINTESTINAL SYNTHETIC EPITHELIAL LININGS FABP2, SLC10A2, FABP6 FABP4 524/4885CDK1 2604/4885CA1 1690/4885
US-20260071218-A1 Oral Delivery of Antisense Conjugates Targeting PCSK9 PCSK9, ALPI, SLC10A2 FABP4 889/4885CDK1 3743/4885CA1 1982/4885
US-20050250852-A1 Polymorphs of sodium 4-[(4-chloro-2-hydroxybenzoyl) amino] butanoate SLC5A1, SLC2A4, SLC2A3 FABP4 15/4885CDK1 2844/4885CA1 4019/4885
US-20240067965-A1 ORAL DELIVERY OF ANTISENSE CONJUGATES TARGETING PCSK9 PCSK9, SCD5, PCSK7 FABP4 1506/4885CDK1 2420/4885CA1 2704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.