Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5435573 | 0.99 | SIGMAR1 (0.40) | SIGMAR1KDM4ESMN1; SMN2CYP1A2P2RY14 | |
| SCHEMBL5433734 | 0.98 | SIGMAR1 (0.40) | SIGMAR1KDM4ESMN1; SMN2CYP1A2P2RY14 | |
| SCHEMBL3975810 | 0.95 | MTNR1A (0.41) | SIGMAR1KDM4ESMN1; SMN2CYP1A2P2RY14 | |
| SCHEMBL4134781 | 0.92 | DDB1 (0.40) | SIGMAR1KDM4ESMN1; SMN2CYP1A2P2RY14 | |
| SCHEMBL5433730 | 0.90 | SIGMAR1 (0.37) | SIGMAR1SMN1; SMN2CYP1A2ALDH1A1MEN1 | |
| SCHEMBL4169255 | 0.88 | SIGMAR1 (0.38) | SIGMAR1P2RY14GSK3BALDH1A1DRD2 | |
| SCHEMBL4183931 | 0.86 | SIGMAR1 (0.37) | SIGMAR1KDM4EP2RY14GSK3BMEN1 | |
| SCHEMBL3975813 | 0.85 | MTNR1A (0.40) | SIGMAR1SMN1; SMN2CYP1A2ALDH1A1MEN1 | |
| SCHEMBL4183936 | 0.85 | SIGMAR1 (0.37) | SIGMAR1KDM4EP2RY14GSK3BMEN1 | |
| SCHEMBL4178090 | 0.83 | SIGMAR1 (0.37) | SIGMAR1SMN1; SMN2CYP1A2P2RY14GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070293472-A1 | Novel 14 and 15 Membered Ring Compounds | GLAXO GROUP LIMITED (GB) | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293472-A1 | Novel 14 and 15 Membered Ring Compounds | IL17A, CYP51A1, IL15 | SIGMAR1 4347/4885KDM4E 3390/4885SMN1; SMN2 4245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.