SCHEMBL543499

SCHEMBL543499

Clc1cc2cc3cc4cc5cc(Cl)c(Cl)cc5cc4cc3cc2cc1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 6/20 0.53
MAPK1 P28482 1/20 0.53
FLT1 P17948 1/20 0.41
TSHR P16473 4/20 0.39
HSD17B10 Q99714 3/20 0.39
HPGD P15428 2/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 2/20 0.38
ALDH1A1 P00352 2/20 0.35
GAA P10253 1/20 0.35
MAPK13 O15264 1/20 0.35
CDK1 P06493 1/20 0.35
PIM1 P11309 1/20 0.35
DYRK1A Q13627 1/20 0.35
PIM3 Q86V86 1/20 0.35
CLK4 Q9HAZ1 1/20 0.35
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5792991 0.95 AHR (0.47) AHRMAPK1FLT1TSHRHSD17B10
SCHEMBL5051947 0.83 CYP2A6 (0.50) AHRMAPK1TSHRHSD17B10HPGD
SCHEMBL811102 0.83 AHR (0.40) AHRMAPK1FLT1TSHRHSD17B10
SCHEMBL11030888 0.83 CYP2A6 (0.50) AHRMAPK1TSHRHSD17B10HPGD
SCHEMBL10691404 0.78 GAA (0.50) AHRMAPK1FLT1TSHRTP53
SCHEMBL811040 0.78 CD44 (0.39) AHRMAPK1FLT1TSHRHSD17B10
SCHEMBL22863557 0.78 AHR (0.35) AHRMAPK1FLT1TSHRHSD17B10
SCHEMBL27765036 0.76 HSD17B10 (0.38) AHRMAPK1TSHRHSD17B10HPGD
SCHEMBL348913 0.75 AHR (0.67) AHRMAPK1FLT1TSHRHSD17B10
SCHEMBL8557932 0.73 CYP2A6 (0.62) AHRMAPK1TSHRHSD17B10TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1719749-B1 POLYACENE COMPOUND AND ORGANIC SEMICONDUCTOR THIN FILM ASAHI CHEMICAL IND (JP) 2016-08-24 EP disclosed
US-8236998-B2 Polyacene compound and organic semiconductor thin film ASAHI KASEI CORPORATION (JP) 2012-08-07 US disclosed
US-20120108850-A1 POLYACENE COMPOUND AND ORGANIC SEMICONDUCTOR THIN FILM NAGATA KAZUTO (JP) 2012-05-03 US disclosed
EP-1724028-B1 METHOD FOR PREPARING THIN FILM OF CONDENSED POLYCYCLC AROMATIC COMPOUND ASAHI CHEMICAL IND (JP) 2012-02-29 EP disclosed
US-8110714-B2 High mobility, solubility, oxidation resistance; transistor; drain electrodes ASAHI KASEI CORPORATION (JP) 2012-02-07 US disclosed
CN-1922123-B Polyacene compound and organic semiconductor thin film ASAHI KASEI FIBERS CORPERATION 2010-05-05 CN disclosed
US-7595093-B2 Condensed polycyclic aromatic compound thin film and method for preparing condensed polycyclic aromatic compound thin film ASAHI KASEI CORPORATION (JP) 2009-09-29 US disclosed
CN-101412651-A Pentacenes and derivatives thereof, as well as thereof UNIV BEIJING CHEMICAL (CN) 2009-04-22 CN disclosed
US-20080061287-A1 Polyacene Compound And Organic Semiconductor Thin Film ASAHI KASEI CORPORATION (JP) 2008-03-13 US disclosed
US-20070184574-A1 Condensed polycyclic aromatic compound thin film and method for preparing condensed polycyclic aromatic compound thin film ASAHI KASEI CORPORATION (JP) 2007-08-09 US disclosed
CN-1922123-A Polyacene compound and organic semiconductor thin film ASAHI CHEMICAL CORP (JP) 2007-02-28 CN disclosed
EP-1724028-A1 THIN FILM OF CONDENSED POLYCYCLC AROMATIC COMPOUND, AND METHOD FOR PREPARING THIN FILM OF CONDENSED POLYCYCLC AROMATIC COMPOUND Asahi Kasei Kabushiki Kaisha, Ltd. (JP) 2006-11-22 EP disclosed
EP-1719749-A1 POLYACENE COMPOUND AND ORGANIC SEMICONDUCTOR THIN FILM Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2006-11-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108850-A1 POLYACENE COMPOUND AND ORGANIC SEMICONDUCTOR THIN FILM ZRANB2, PUF60, ZKSCAN2 AHR 1540/4885MAPK1 1552/4885FLT1 2992/4885
US-20080061287-A1 Polyacene Compound And Organic Semiconductor Thin Film ZRANB2, PUF60, ZKSCAN2 AHR 1540/4885MAPK1 1552/4885FLT1 2992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.