SCHEMBL5435012

SCHEMBL5435012

CC(C)(C)c1ccccc1[CH]c1ccccc1C(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
TDP1 Q9NUW8 3/20 0.48
TSHR P16473 2/20 0.48
CA2 P00918 1/20 0.44
ALOX12 P18054 2/20 0.44
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
KIF11 P52732 1/20 0.36
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
THRB P10828 2/20 0.33
LMNA P02545 1/20 0.33
BLM P54132 1/20 0.33
MAPT P10636 3/20 0.33
PLA2G1B P04054 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
NFKB1 P19838 1/20 0.32
KDM4E B2RXH2 2/20 0.32
GRIN2D O15399 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3452696 0.86 ALDH1A1 (0.41) ALDH1A1TDP1TSHRCA2ALOX12
SCHEMBL596277 0.84 ALDH1A1 (0.48) ALDH1A1TDP1TSHRCA2ALOX12
SCHEMBL8576453 0.84 ALDH1A1 (0.48) ALDH1A1TDP1TSHRCA2ALOX12
SCHEMBL2095450 0.84 CYP3A4 (0.38) ALDH1A1TDP1TSHRCA2ALOX12
SCHEMBL15525730 0.82 ALDH1A1 (0.46) ALDH1A1TDP1TSHRCA2ALOX12
SCHEMBL27805 0.80 ALDH1A1 (0.50) ALDH1A1TDP1TSHRCA2ALOX12
SCHEMBL5868149 0.80 ALDH1A1 (0.44) ALDH1A1TDP1TSHRCA2ALOX12
SCHEMBL536090 0.80 LMNA (0.55) ALDH1A1TDP1TSHRCA2ALOX12
SCHEMBL29801228 0.80 ALDH1A1 (0.50) ALDH1A1TDP1TSHRCA2ALOX12
SCHEMBL18601365 0.80 ALDH1A1 (0.44) ALDH1A1TDP1TSHRCA2ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118176220-A Catalyst for olefin polymerization and process for producing olefin polymer 国立大学法人东京大学 2024-06-11 CN disclosed
US-20070189058-A1 Molecular system and method for reversibly switching the same between four states HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2007-08-16 US disclosed
US-20070112103-A1 Molecular system and method for reversibly switching the same HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2007-05-17 US disclosed