Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5435012 | 0.84 | ALDH1A1 (0.48) | ALDH1A1TDP1TSHRCA2ALOX12 | |
| SCHEMBL8576453 | 0.84 | ALDH1A1 (0.48) | ALDH1A1TDP1TSHRCA2ALOX12 | |
| SCHEMBL10382469 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TDP1TSHRCA2ALOX12 | |
| SCHEMBL31348027 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TDP1TSHRCA2ALOX12 | |
| SCHEMBL15525730 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TDP1TSHRCA2ALOX12 | |
| SCHEMBL676429 | 0.81 | ALOX12 (0.43) | ALDH1A1TDP1TSHRCA2ALOX12 | |
| SCHEMBL29801228 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRCA2ALOX12 | |
| SCHEMBL27805 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRCA2ALOX12 | |
| SCHEMBL5868149 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TDP1TSHRCA2ALOX12 | |
| SCHEMBL18601365 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TDP1TSHRCA2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180030200-A1 | FLUORINE ATOM-CONTAINING POLYMER AND USE OF SAME | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-02-01 | — | — | US | disclosed |
| EP-3263622-A1 | FLUORINE ATOM-CONTAINING POLYMER AND USE OF SAME | Nissan Chemical Industries, Ltd. (JP) | 2018-01-03 | — | — | EP | disclosed |
| EP-1990682-B1 | Electrophotographic photoreceptor, and image forming apparatus and process cartridge using the same | RICOH CO LTD (JP) | 2015-01-21 | — | — | EP | disclosed |
| US-8895560-B2 | Opioid antagonists | ADOLOR CORPORATION (US) | 2014-11-25 | — | — | US | disclosed |
| US-20140186951-A1 | NOVEL OPIOID ANTAGONISTS | ADOLOR CORPORATION (US) | 2014-07-03 | — | — | US | disclosed |
| US-20130317035-A1 | NOVEL OPIOID ANTAGONISTS | ADOLOR CORPORATION (US) | 2013-11-28 | — | — | US | disclosed |
| US-8580788-B2 | Opioid antagonists | ADOLOR CORPORATION (US) | 2013-11-12 | — | — | US | disclosed |
| EP-1940412-B1 | NOVEL OPIOID ANTAGONISTS | ADOLOR CORP (US) | 2013-01-23 | — | — | EP | disclosed |
| US-8278323-B2 | Opioid antagonists | ADOLOR CORPORATION (US) | 2012-10-02 | — | — | US | disclosed |
| US-20120231543-A1 | NOVEL OPIOID ANTAGONISTS | ADOLOR CORPORATION (US) | 2012-09-13 | — | — | US | disclosed |
| EP-1367439-A1 | Radiation-sensitive composition | FUJI PHOTO FILM CO., LTD. (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6630280-B1 | Resin and compound that generates an arylsulfonic acid when exposed to actinic radiation; sensitivity; resolution; smoothness | FUJI PHOTO FILM CO., LTD. (JP) | 2003-10-07 | — | — | US | disclosed |
| US-20030134221-A1 | Positive resist composition | FUJI PHOTO FILM CO., LTD. | 2003-07-17 | — | — | US | disclosed |
| US-20030108811-A1 | Positive resist composition | FUJI PHOTO FILM CO., LTD. | 2003-06-12 | — | — | US | disclosed |
| EP-1180765-A1 | Optical recording medium and porphycene compound | Mitsui Chemicals, Inc. (JP) | 2002-02-20 | — | — | EP | disclosed |
| US-20020012866-A1 | Positive photoresist composition | FUJIFILM CORPORATION (JP) | 2002-01-31 | — | — | US | disclosed |
| US-6106999-A | SENSITIVITY TO GENERAL-PURPOSE VISIBLE LIGHT LASER, SO THAT HIGH-SPEED SCANNING EXPOSURE IS POSSIBLE BY LASER, AND EXTREMELY FINE HIGH RESOLUTION CAN BE OBTAINED; CAN BE USED FOR COATING OR PRINTING UNDER SAFELIGHT IRRADIATING CONDITIONS | MITSUI CHEMICALS (JP) | 2000-08-22 | — | — | US | disclosed |
| EP-0434079-B1 | N,N'-hydrocarbylenebis(N-hals-substituted amic acid hydrazides) and their derivatives | ATOCHEM NORTH AMERICA (US) | 1995-09-20 | — | — | EP | disclosed |
| CN-1047859-A | Benzo cycloalkane derivatives and preparation method thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1990-12-19 | — | — | CN | disclosed |
| EP-0399422-A1 | Benzocycloalkane derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120231543-A1 | NOVEL OPIOID ANTAGONISTS | OPRK1, OPRM1, OPRL1 | ALDH1A1 761/4885TDP1 4543/4885TSHR 722/4885 |
| US-20130317035-A1 | NOVEL OPIOID ANTAGONISTS | OPRK1, OPRM1, OPRL1 | ALDH1A1 761/4885TDP1 4543/4885TSHR 722/4885 |
| US-20180030200-A1 | FLUORINE ATOM-CONTAINING POLYMER AND USE OF SAME | AFF2, AFF1, AFF4 | ALDH1A1 2629/4885TDP1 962/4885TSHR 2722/4885 |
| US-20140186951-A1 | NOVEL OPIOID ANTAGONISTS | OPRK1, OPRM1, OPRL1 | ALDH1A1 761/4885TDP1 4543/4885TSHR 722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.