Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | FBP1 | P09467 | 3/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5429900 | 1.00 | ALDH1A1 (0.53) | ALDH1A1CYP3A4MAPTFBP1PIN1 | |
| SCHEMBL14359432 | 1.00 | ALDH1A1 (0.53) | ALDH1A1CYP3A4MAPTFBP1PIN1 | |
| SCHEMBL578529 | 0.84 | ALDH1A1 (0.56) | ALDH1A1CYP3A4MAPTFBP1PIN1 | |
| SCHEMBL5429907 | 0.81 | ALDH1A1 (0.48) | ALDH1A1CYP3A4MAPTCYP2C19LMNA | |
| SCHEMBL14350851 | 0.81 | ALDH1A1 (0.52) | ALDH1A1CYP3A4FBP1PIN1MMP8 | |
| SCHEMBL14388561 | 0.79 | MAPT (0.46) | ALDH1A1CYP3A4MAPTPIN1MAPK1 | |
| SCHEMBL14338578 | 0.78 | ALDH1A1 (0.51) | ALDH1A1CYP3A4MAPTFBP1PIN1 | |
| SCHEMBL14350805 | 0.78 | ALDH1A1 (0.51) | ALDH1A1CYP3A4MAPTFBP1PIN1 | |
| SCHEMBL14338567 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CYP3A4MAPTFBP1PIN1 | |
| SCHEMBL14338569 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CYP3A4MAPTFBP1PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276145-A1 | Method of Preparing a Ring Compound Having Two Adjacent Chiral Centers | ICOS CORPORATION (US) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276145-A1 | Method of Preparing a Ring Compound Having Two Adjacent Chiral Centers | NISCH, NDC1, SUCLG2 | ALDH1A1 1567/4885CYP3A4 902/4885MAPT 3548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.