SCHEMBL5437352

SCHEMBL5437352

CCCCC(OCC)N(C)C

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.33
THRB P10828 1/20 0.33
OPRM1 P35372 1/20 0.32
LMNA P02545 1/20 0.32
ALDH1A1 P00352 3/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5432779 0.93 OPRM1 (0.41) DNM1THRBOPRM1LMNA
SCHEMBL5442791 0.91 OPRM1 (0.39) DNM1THRBOPRM1LMNA
SCHEMBL5436774 0.91 OPRM1 (0.39) DNM1THRBOPRM1LMNA
SCHEMBL5432519 0.91 OPRM1 (0.39) DNM1THRBOPRM1LMNA
SCHEMBL5444717 0.91 OPRM1 (0.39) DNM1THRBOPRM1LMNA
Hydrochloric Acid SCHEMBL28433848 0.89 DNM1 (0.38) DNM1THRBOPRM1LMNA
SCHEMBL5442524 0.85 THRB (0.36) THRBLMNA
SCHEMBL28685285 0.80 TSHR (0.30) DNM1
SCHEMBL4543524 0.78 DNM1 (0.35) DNM1ALDH1A1TDP1
SCHEMBL10382328 0.77 TSHR (0.38) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2500368-A2 Catalyst and process for producing a rigid polyurethane foam Tosoh Corporation (JP) 2012-09-19 EP disclosed
US-20070043132-A1 Catalyst and process for producing a rigid polyurethane foam TOSOH CORPORATION (JP) 2007-02-22 US disclosed
US-20040082465-A1 Catalyst and process for producing a rigid polyurethane foam TOSOH CORPORATION (JP) 2004-04-29 US disclosed
EP-1382624-A1 Catalyst and process for producing a rigid polyurethane foam Tosoh Corporation (JP) 2004-01-21 EP disclosed