Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL549193 | 0.81 | SMN1; SMN2 (0.49) | NPC1RAB9ACHRNA7KDM4EMAPT | |
| SCHEMBL28852004 | 0.76 | CHRNA7 (0.78) | NPC1CHRNA7KDM4EMAPTGAA | |
| SCHEMBL28269640 | 0.74 | MAPT (0.50) | NPC1RAB9AKDM4EMAPTGAA | |
| SCHEMBL20376700 | 0.74 | MAPT (0.55) | CHRNA7KDM4EMAPTGAARAD52 | |
| SCHEMBL2876202 | 0.72 | ADRB1 (0.52) | KDM4EKCNH2HRH3TAAR1HSD17B10 | |
| SCHEMBL12319455 | 0.69 | CHRNA7 (0.79) | RAB9ACHRNA7KDM4EMAPTGAA | |
| SCHEMBL394300 | 0.69 | TAAR1 (0.76) | NPC1RAB9AKDM4EMAPTTAAR1 | |
| SCHEMBL30487922 | 0.67 | TAAR1 (0.73) | NPC1RAB9AKDM4EMAPTTAAR1 | |
| SCHEMBL2759898 | 0.67 | TAAR1 (0.66) | NPC1RAB9AKDM4EMAPTGAA | |
| SCHEMBL1101883 | 0.64 | CHRNA7 (1.00) | CHRNA7KDM4EMAPTGAARAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197957-A1 | Implantable sensors, implantable pumps and anti-scarring drug combinations | HUNTER WILLIAM L | 2007-08-23 | — | — | US | disclosed |