Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.78 |
| ▸ | DRD2 | P14416 | 3/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101883 | 0.88 | CHRNA7 (1.00) | CHRNA7DRD2SIGMAR1KCNH2DRD4 | |
| Hydrochloric Acid SCHEMBL11555541 | 0.86 | CHRNA7 (0.96) | CHRNA7DRD2SIGMAR1KCNH2DRD4 | |
| SCHEMBL20376700 | 0.82 | MAPT (0.55) | CHRNA7DRD2SIGMAR1KCNH2KDM4E | |
| SCHEMBL27822324 | 0.82 | SIGMAR1 (0.64) | CHRNA7DRD2SIGMAR1KCNH2KDM4E | |
| SCHEMBL15304372 | 0.81 | CHRNA7 (0.85) | CHRNA7DRD2SIGMAR1KCNH2DRD4 | |
| Isothiocyanate SCHEMBL2895505 | 0.78 | CHRNA7 (0.79) | CHRNA7DRD2SIGMAR1KCNH2DRD4 | |
| SCHEMBL1006036 | 0.78 | LMNA (0.54) | CHRNA7DRD2SIGMAR1KCNH2DRD4 | |
| SCHEMBL12319455 | 0.77 | CHRNA7 (0.79) | CHRNA7DRD2SIGMAR1DRD4KDM4E | |
| SCHEMBL549193 | 0.77 | SMN1; SMN2 (0.49) | CHRNA7DRD2SIGMAR1KDM4EMAPT | |
| SCHEMBL3453669 | 0.76 | DRD2 (1.00) | CHRNA7DRD2SIGMAR1KCNH2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989137-B | Chiral imine-containing quinoline imidazoline compound and metal complex thereof, preparation method and application | 浙江大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-114989137-A | Chiral quinoline imidazoline compound containing imine, metal complex thereof, preparation method and application | 浙江大学 | 2022-09-02 | — | — | CN | disclosed |