SCHEMBL543803

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Hydrochloric Acid SCHEMBL544385	0.99	ALDH1A1 (0.48)	ALDH1A1KDM4EHPGDNPSR1LMNA
	SCHEMBL26123802	0.91	ALDH1A1 (0.54)	ALDH1A1KDM4EHPGDNPSR1LMNA
	SCHEMBL544399	0.85	HTR1A (0.47)	HTR1AHTR1DHTR1BHTR1FMAP3K5
	SCHEMBL13841046	0.85	HTR1A (0.61)	ALDH1A1KDM4EHPGDNPSR1LMNA
	SCHEMBL3962847	0.83	JAK2 (0.44)	HTR1AHTR1DHTR1BHTR1FLCK
	SCHEMBL10079148	0.80	HTR1A (0.40)	ALDH1A1KDM4EHPGDNPSR1LMNA
	SCHEMBL15970928	0.78	ALDH1A1 (0.51)	ALDH1A1KDM4EHPGDNPSR1LMNA
	SCHEMBL5872012	0.78	SCD (0.48)	ALDH1A1NPSR1RXFP1SMN1; SMN2HTR1A
	SCHEMBL27721881	0.78	KDM4C (0.40)	ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2
	SCHEMBL27519949	0.77	ALDH1A1 (0.53)	ALDH1A1KDM4EHPGDNPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.