Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.71 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.69 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.69 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.69 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.69 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.69 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.69 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.69 |
| ▸ | EGFR | P00533 | 2/20 | 0.68 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.64 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.63 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.63 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.63 |
| ▸ | PRKCG | P05129 | 1/20 | 0.63 |
| ▸ | PRKACA | P17612 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2062871 | 0.95 | HDAC1 (0.73) | EPHX2NR1H4HDAC1HDAC6HDAC3 | |
| SCHEMBL2924662 | 0.88 | HDAC6 (0.74) | EPHX2NR1H4HDAC1HDAC6HDAC3 | |
| SCHEMBL9416580 | 0.86 | HDAC6 (0.64) | EPHX2NR1H4HDAC1HDAC6HDAC3 | |
| SCHEMBL539059 | 0.84 | EPHX2 (0.84) | EPHX2NR1H4HDAC1HDAC6HDAC3 | |
| SCHEMBL11711200 | 0.84 | RAB9A (0.66) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL457082 | 0.84 | HDAC6 (0.79) | EPHX2NR1H4HDAC1HDAC6HDAC2 | |
| SCHEMBL29184442 | 0.82 | HDAC6 (0.76) | EPHX2NR1H4HDAC1HDAC6HDAC2 | |
| Hydrochloric Acid SCHEMBL3757721 | 0.82 | HDAC6 (0.76) | EPHX2NR1H4HDAC1HDAC6HDAC2 | |
| SCHEMBL6386658 | 0.82 | HDAC6 (1.00) | EPHX2NR1H4HDAC1HDAC6HDAC3 | |
| SCHEMBL10099575 | 0.81 | NR1H4 (0.84) | EPHX2NR1H4HDAC1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007530524-A | — | — | 2007-11-01 | — | — | JP | claimed |
| EP-1730103-A1 | FORMAMIDE DERIVATIVES USEFUL AS ADRENOCEPTOR | Pfizer Limited (GB) | 2006-12-13 | — | — | EP | claimed |
| WO-2005092840-A1 | FORMAMIDE DERIVATIVES USEFUL AS ADRENOCEPTOR | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | claimed |
| EP-1730103-A1 | FORMAMIDE DERIVATIVES USEFUL AS ADRENOCEPTOR | Pfizer Limited (GB) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005092840-A1 | FORMAMIDE DERIVATIVES USEFUL AS ADRENOCEPTOR | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | disclosed |