SCHEMBL539059

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11900090	0.92	HDAC6 (0.85)	EPHX2NR1H4HDAC6HDAC2HDAC8
	SCHEMBL3025457	0.91	HDAC6 (0.91)	EPHX2NR1H4HDAC6HDAC2HDAC8
	SCHEMBL6386658	0.90	HDAC6 (1.00)	EPHX2NR1H4HDAC6HDAC2HDAC8
	SCHEMBL1912347	0.89	HDAC6 (0.80)	EPHX2NR1H4HDAC6HDAC2HDAC8
	SCHEMBL1926318	0.89	EPHX2 (0.77)	EPHX2NR1H4HDAC6HDAC2HDAC8
	SCHEMBL539269	0.89	MMP13 (1.00)	EPHX2NR1H4HDAC6HDAC2HDAC8
	SCHEMBL4981515	0.89	EPHX2 (0.77)	EPHX2NR1H4HDAC6HDAC2HDAC8
	SCHEMBL1927145	0.89	EPHX2 (0.77)	EPHX2NR1H4HDAC6HDAC2HDAC8
	SCHEMBL3812691	0.89	ROCK2 (1.00)	EPHX2NR1H4HDAC6HDAC2HDAC8
	SCHEMBL457082	0.88	HDAC6 (0.79)	EPHX2NR1H4HDAC6HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.