Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 8/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5439416 | 0.96 | PRKCA (0.40) | PRKCAMMP12GABRA1GABRG2GABRB3 | |
| SCHEMBL5439417 | 0.89 | GABRA1 (0.34) | PRKCAMMP12GABRA1GABRG2GABRB3 | |
| SCHEMBL5402256 | 0.85 | PRKCA (0.47) | PRKCAMMP12 | |
| SCHEMBL2907228 | 0.82 | PRKCA (0.50) | PRKCAMMP12SCN9ACYP2D6 | |
| SCHEMBL5435258 | 0.79 | PRKCA (0.43) | PRKCAMMP12SCN9APTGER4 | |
| SCHEMBL5448428 | 0.79 | PRKCA (0.47) | PRKCAMMP12 | |
| SCHEMBL14448759 | 0.79 | PRKCA (0.47) | PRKCAMMP12SCN9ACYP3A4CYP2D6 | |
| SCHEMBL393462 | 0.79 | PRKCA (0.45) | PRKCAMMP12SCN9ACYP3A4CYP2D6 | |
| SCHEMBL5783672 | 0.78 | PRKCA (0.46) | PRKCAMMP12SCN9A | |
| SCHEMBL5438990 | 0.77 | PRKCA (0.45) | PRKCAMMP12SCN9ACYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007516158-A | — | — | 2007-06-21 | — | — | JP | claimed |
| EP-1613634-A1 | INDOLE ACETAMIDES AS INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2006-01-11 | — | — | EP | claimed |
| WO-2004087714-A1 | INDOLE ACETAMIDES AS INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2004-10-14 | — | — | WO | claimed |