Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5439760 | 0.96 | PRKCA (0.42) | PRKCAMMP12GABRA1GABRG2GABRB3 | |
| SCHEMBL5439417 | 0.90 | GABRA1 (0.34) | PRKCAMMP12GABRA1GABRG2GABRB3 | |
| SCHEMBL5402256 | 0.82 | PRKCA (0.47) | PRKCAMMP12ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5442306 | 0.81 | PRKCA (0.44) | PRKCAMMP12GABRA1GABRG2GABRB3 | |
| Trifluoroacetic Acid SCHEMBL5439078 | 0.80 | PRKCA (0.42) | PRKCAMMP12CYP3A4CYP2C19CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL5436897 | 0.79 | PRKCA (0.42) | PRKCAMMP12SCN9A | |
| SCHEMBL2907228 | 0.79 | PRKCA (0.50) | PRKCAMMP12CYP2D6SCN9A | |
| SCHEMBL393462 | 0.77 | PRKCA (0.45) | PRKCAMMP12CYP3A4CYP2C19CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL5440751 | 0.76 | PRKCA (0.49) | PRKCAMMP12CYP3A4CYP2C19CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL5435091 | 0.76 | PRKCA (0.38) | PRKCAMMP12CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167447-A1 | Indole acetamides as inhibitors of the hepatitis c virus ns5b polymerase | ISTITUTO DI RICERCHE DI BIOLOGIA DI MOLECULOARE P. ANGELETTI SPA (IT) | 2007-07-19 | — | — | US | claimed |
| US-20070167447-A1 | Indole acetamides as inhibitors of the hepatitis c virus ns5b polymerase | ISTITUTO DI RICERCHE DI BIOLOGIA DI MOLECULOARE P. ANGELETTI SPA (IT) | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167447-A1 | Indole acetamides as inhibitors of the hepatitis c virus ns5b polymerase | IDO1, NAT1, AANAT | PRKCA 4676/4885MMP12 3218/4885GABRA1 3809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.