SCHEMBL5440310

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5424848	0.85	HPGD (0.67)	CYP11B1CYP11B2HPGDLMNATSHR
	SCHEMBL27986640	0.85	HPGD (0.56)	HPGDLMNATSHRALDH1A1MAPT
	SCHEMBL5422107	0.85	MKNK1 (0.58)	CYP11B1CYP11B2HPGDLMNATSHR
	SCHEMBL5437021	0.82	SCN10A (0.52)	CYP11B1CYP11B2HPGDLMNATSHR
	SCHEMBL5424646	0.82	HPGD (0.47)	HPGDLMNATSHRALDH1A1MAPT
	SCHEMBL5430912	0.81	LMNA (0.51)	CYP11B1CYP11B2HPGDLMNATSHR
	SCHEMBL7669610	0.80	ALDH1A1 (0.61)	HPGDLMNAALDH1A1MAPTCYP1A2
	SCHEMBL5430302	0.80	HPGD (0.49)	CYP11B1CYP11B2HPGDLMNATSHR
	SCHEMBL641553	0.79	CYP11B1 (0.60)	CYP11B1CYP11B2ALDH1A1MAPTXDH
	SCHEMBL5418318	0.76	CYP1A2 (0.47)	HPGDLMNATSHRALDH1A1ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.