Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | AXL | P30530 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PI4KA | P42356 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5440532 | 1.00 | RAB9A (0.49) | RAB9ACYP3A4ALDH1A1HSD17B10NPC1 | |
| SCHEMBL13539413 | 0.80 | RAB9A (0.68) | RAB9ACYP3A4ALDH1A1HSD17B10NPC1 | |
| SCHEMBL27522839 | 0.77 | RAB9A (0.62) | RAB9ACYP3A4ALDH1A1HSD17B10NPC1 | |
| SCHEMBL1855355 | 0.77 | CYP3A4 (0.70) | RAB9ACYP3A4ALDH1A1HSD17B10NPC1 | |
| SCHEMBL1855358 | 0.77 | CYP3A4 (0.70) | RAB9ACYP3A4ALDH1A1HSD17B10NPC1 | |
| SCHEMBL13236087 | 0.77 | INSR (0.64) | RAB9ACYP3A4ALDH1A1HSD17B10NPC1 | |
| SCHEMBL2275595 | 0.76 | RAB9A (0.56) | RAB9ACYP3A4ALDH1A1HSD17B10NPC1 | |
| SCHEMBL14538310 | 0.75 | PIK3CA (0.40) | RAB9ACYP3A4ALDH1A1HSD17B10NPC1 | |
| SCHEMBL13699058 | 0.73 | CYP3A4 (0.53) | RAB9ACYP3A4ALDH1A1HSD17B10NPC1 | |
| SCHEMBL334946 | 0.69 | RAB9A (0.66) | RAB9ACYP3A4ALDH1A1HSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070149508-A1 | Six membered heteroaromatic inhibitors targeting resistant kinase mutations | TARGEGEN, INC. (US) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149508-A1 | Six membered heteroaromatic inhibitors targeting resistant kinase mutations | ABL1, KDR, BCR | RAB9A 1849/4885CYP3A4 1786/4885ALDH1A1 3322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.