SCHEMBL544155

SCHEMBL544155

COC(=O)CN=C=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL485846 0.78
SCHEMBL2042195 0.77
SCHEMBL1364810 0.77
Water SCHEMBL27335870 0.76
SCHEMBL9824418 0.76 GAA (0.44)
SCHEMBL3610450 0.76 KEAP1 (0.34)
SCHEMBL10674424 0.76 LMNA (0.38)
SCHEMBL10671098 0.74 NAAA (0.35)
SCHEMBL13664664 0.74 TSHR (0.54)
SCHEMBL23709964 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116053577-B Polyurea and polythiourea super-ion solid electrolyte and preparation method and application thereof 华南理工大学 2026-05-12 CN claimed
CN-112531211-B Electrolyte, preparation method thereof and lithium ion battery 惠州亿纬锂能股份有限公司 2022-06-14 CN claimed
CN-112531211-A Electrolyte, preparation method thereof and lithium ion battery 惠州亿纬锂能股份有限公司 2021-03-19 CN claimed
EP-3953342-B1 IMPROVED INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX AND METHODS FOR USE OF THE SAME UNIV MIAMI (US) 2025-09-24 EP disclosed
US-12275725-B2 Inhibitors of the notch transcriptional activation complex and methods for use of the same UNIVERSITY OF MIAMI (US) 2025-04-15 US disclosed
WO-2023086580-A2 MULTICYCLIC COMPOUNDS ATLEE BIOTECH, INC. (US) 2023-05-19 WO disclosed
US-20220194932-A1 IMPROVED INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX AND METHODS FOR USE OF THE SAME STEMSYNERGY THERAPEUTICS, INC. 2022-06-23 US disclosed
EP-3953342-A1 IMPROVED INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX AND METHODS FOR USE OF THE SAME University of Miami (US) 2022-02-16 EP disclosed
WO-2020209933-A1 IMPROVED INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX AND METHODS FOR USE OF THE SAME UNIVERSITY OF MIAMI (US) 2020-10-15 WO disclosed
EP-2352201-B1 DYE, PHOTOELECTRIC CONVERSION ELEMENT AND PHOTOELECTROCHEMICAL CELL EACH COMPRISING THE DYE, AND PROCESS FOR PRODUCING DYE FUJIFILM CORP (JP) 2018-10-17 EP disclosed
US-9424998-B2 Dye, photoelectric conversion element using the same, photoelectrochemical cell, and method of producing dye FUJIFILM CORPORATION (JP) 2016-08-23 US disclosed
EP-0348513-A1 STYRENE DERIVATIVE, POLYSTYRENE DERIVATIVE COMPRISING THE SAME, PROCESS FOR PREPARING SAID POLYSTYRENE DERIVATIVE, AND ULTRAVIOLET ABSORBER COMPRISING SAID STYRENE DERIVATIVE OR POLYSTYRENE DERIVATIVE EARTH CHEMICAL CO., LTD. (JP) 1990-01-03 EP disclosed
US-4772717-A Novel process for the preparation of biotin PFIZER INC. (US) 1988-09-20 US disclosed
EP-0094776-B1 NOVEL PROCESS FOR THE PREPARATION OF BIOTIN PFIZER INC. (US) 1988-06-22 EP disclosed
US-4732988-A Bicyclic precursors for the preparation of biotin PFIZER INC. (US) 1988-03-22 US disclosed
US-4694087-A Imidazolidinone precursors for the preparation of biotin PFIZER INC. (US) 1987-09-15 US disclosed
US-4631345-A Thiazole precursors for the preparation of biotin PFIZER INC. (US) 1986-12-23 US disclosed
US-4581459-A Process for the preparation of biotin PFIZER INC. (US) 1986-04-08 US disclosed
US-4468516-A Process for the preparation of biotin PFIZER INC. (US) 1984-08-28 US disclosed
EP-0094776-A2 Novel process for the preparation of biotin PFIZER INC. (US) 1983-11-23 EP disclosed