Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5441969 | 0.71 | EGFR (0.43) | HTR6FEN1MAPTALDH1A1PTGS2 | |
| SCHEMBL14136047 | 0.68 | GAA (0.59) | HTR6MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8471385 | 0.65 | ALDH1A1 (0.64) | HTR6MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL6575496 | 0.64 | HTR6 (0.56) | HTR6MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28834578 | 0.64 | TTK (0.50) | HTR6FEN1ALDH1A1PTGS2 | |
| Hydrochloric Acid SCHEMBL6575484 | 0.63 | HTR6 (0.54) | HTR6MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7206333 | 0.63 | HTR6 (0.58) | HTR6MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL6038429 | 0.63 | HTR6 (0.67) | HTR6MAPT | |
| SCHEMBL1108964 | 0.62 | TYMS (0.48) | HTR6FEN1MAPTPOLBALDH1A1 | |
| SCHEMBL11686034 | 0.62 | HTR6 (0.44) | HTR6FEN1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070004684-A1 | Alpha-Carbolines as CDK-1 inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004684-A1 | Alpha-Carbolines as CDK-1 inhibitors | CDKL1, CDK1, CCNA1 | HTR6 2608/4885FEN1 1081/4885MAPT 2266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.