Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30166994 | 0.82 | HTR6 (0.42) | TYMSALDH1A1POLBSMN1; SMN2MAPT | |
| SCHEMBL8501874 | 0.81 | NPBWR1 (0.47) | ALDH1A1HPGDMEN1KMT2AHSP90AA1 | |
| SCHEMBL10896181 | 0.80 | NPC1 (0.48) | ALDH1A1POLBSMN1; SMN2MAPTRAB9A | |
| SCHEMBL14493326 | 0.80 | MAPT (0.51) | ALDH1A1MAPTHPGDHSD17B10MEN1 | |
| SCHEMBL4318643 | 0.80 | HDAC6 (0.46) | TYMSALDH1A1POLBSMN1; SMN2MAPT | |
| SCHEMBL12213875 | 0.79 | NPBWR1 (0.54) | ALDH1A1POLBSMN1; SMN2MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL32662723 | 0.78 | ALDH1A1 (0.44) | TYMSALDH1A1POLBSMN1; SMN2MAPT | |
| SCHEMBL11371864 | 0.77 | TAS2R14 (0.54) | ALDH1A1SMN1; SMN2HTR6MEN1KMT2A | |
| SCHEMBL10627091 | 0.76 | LMNA (0.56) | ALDH1A1POLBSMN1; SMN2HPGDMAPK1 | |
| SCHEMBL15381368 | 0.76 | POLB (0.54) | ALDH1A1POLBSMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153385-B2 | Target protein and target gene in drug designing and screening method | REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) | 2012-04-10 | — | — | US | disclosed |
| US-8153385-B2 | Target protein and target gene in drug designing and screening method | REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) | 2012-04-10 | — | — | US | disclosed |
| US-20100136524-A1 | TARGET PROTEIN AND TARGET GENE IN DRUG DESIGNING AND SCREENING METHOD | REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
| US-20100136524-A1 | TARGET PROTEIN AND TARGET GENE IN DRUG DESIGNING AND SCREENING METHOD | REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100136524-A1 | TARGET PROTEIN AND TARGET GENE IN DRUG DESIGNING AND SCREENING METHOD | CHP1, CMA1, CARHSP1 | TYMS 3716/4885ALDH1A1 3307/4885POLB 4610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.