Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.94 |
| ▸ | CASP7 | P55210 | 3/20 | 0.75 |
| ▸ | CASP3 | P42574 | 2/20 | 0.75 |
| ▸ | CASP6 | P55212 | 2/20 | 0.75 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.75 |
| ▸ | CASP2 | P42575 | 1/20 | 0.75 |
| ▸ | PARP1 | P09874 | 4/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.56 |
| ▸ | FER | P16591 | 1/20 | 0.56 |
| ▸ | LTK | P29376 | 1/20 | 0.56 |
| ▸ | CDK8 | P49336 | 1/20 | 0.56 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.56 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.56 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 5/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalimide SCHEMBL5955076 | 1.00 | GSK3B (0.94) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL7065407 | 1.00 | GSK3B (0.94) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL1835394 | 1.00 | GSK3B (0.94) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL10192661 | 0.97 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL11040503 | 0.97 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL30125197 | 0.97 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL29366030 | 0.97 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL64 | 0.97 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL7771670 | 0.97 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL28226707 | 0.97 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186739-B2 | Stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | IMMUPHARMA (FRANCE) SA (FR) | 2007-03-06 | — | — | US | disclosed |
| US-7060845-B2 | Stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | NEOMPS (FR) | 2006-06-13 | — | — | US | disclosed |
| US-20050159584-A1 | Novel stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2005-07-21 | — | — | US | disclosed |
| US-20050159585-A1 | Novel stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2005-07-21 | — | — | US | disclosed |
| US-20020143191-A1 | Novel stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | UREKA SARL (FR) | 2002-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159584-A1 | Novel stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | CPS1, ASNS, ACMSD | GSK3B 4786/4885CASP7 473/4885CASP3 184/4885 |
| US-20050159585-A1 | Novel stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | CPS1, ASNS, ACMSD | GSK3B 4786/4885CASP7 473/4885CASP3 184/4885 |
| US-20020143191-A1 | Novel stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | CPS1, ACMSD, PROC | GSK3B 4749/4885CASP7 320/4885CASP3 219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.