Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284851 | 0.89 | MAPT (0.65) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL3248111 | 0.87 | GSTP1 (0.67) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL1029702 | 0.85 | ALDH1A1 (0.67) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL1703820 | 0.84 | MAPT (0.59) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL18009919 | 0.83 | MAPT (0.66) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL9561179 | 0.82 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1MAPTHTT | |
| Fluorescein Diacetate SCHEMBL31658971 | 0.81 | MAPT (1.00) | MEN1KMT2AALDH1A1MAPTHTT | |
| Fluorescein Diacetate SCHEMBL29453229 | 0.81 | MAPT (1.00) | MEN1KMT2AALDH1A1MAPTHTT | |
| Fluorescein Diacetate SCHEMBL29353816 | 0.81 | MAPT (1.00) | MEN1KMT2AALDH1A1MAPTHTT | |
| Fluorescein Diacetate SCHEMBL1028369 | 0.81 | MAPT (1.00) | MEN1KMT2AALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070111973-A1 | TREATMENT OF TUMOURS | HAGSTROM TOMAS | 2007-05-17 | — | — | US | disclosed |
| US-20050192262-A1 | Treatment of tumours | HAGSTROM, TOMAS (SE) | 2005-09-01 | — | — | US | disclosed |
| EP-1379542-A2 | TREATMENT OF TUMOURS | Hagström, Tomas (SE) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002072003-A2 | USE OF STEROID DERIVATIVES FOR THE TREATMENT OF A BENIGHN AND/OR MALIGNANT TUMOUR | HAGSTROEM TOMAS (SE) | 2002-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192262-A1 | Treatment of tumours | SULT2A1, SULT1A1, HSD17B11 | MEN1 4560/4885KMT2A 3917/4885ALDH1A1 448/4885 |
| US-20070111973-A1 | TREATMENT OF TUMOURS | SULT2A1, SULT1A1, SULT1E1 | MEN1 4666/4885KMT2A 2806/4885ALDH1A1 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.