⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441 | 0.79 | — | — | |
| SCHEMBL9111678 | 0.76 | PKM (0.45) | — | |
| SCHEMBL1036290 | 0.74 | — | — | |
| SCHEMBL4963218 | 0.74 | — | — | |
| SCHEMBL1268284 | 0.70 | — | — | |
| SCHEMBL8963903 | 0.69 | HRH3 (0.73) | — | |
| SCHEMBL17772699 | 0.69 | ALDH1A1 (0.41) | — | |
| SCHEMBL890317 | 0.69 | — | — | |
| SCHEMBL27699577 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL7090498 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10222511-B2 | Optical article comprising a double-layer abrasion and scratch resistant coating and method for production thereof | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2019-03-05 | — | — | US | disclosed |
| US-20170003420-A1 | OPTICAL ARTICLE COMPRISING A DOUBLE-LAYER ABRASION AND SCRATCH RESISTANT COATING AND METHOD FOR PRODUCTION THEREOF | ESSILOR INTERNATIONAL (FR) | 2017-01-05 | — | — | US | disclosed |
| EP-2092377-B1 | OPTICAL ARTICLE COMPRISING A DOUBLE-LAYER ABRASION AND SCRATCH RESISTANT COATING AND METHOD FOR PRODUCTION THEREOF | ESSILOR INT (FR) | 2012-02-08 | — | — | EP | disclosed |
| CN-101553743-B | Optical article comprising a double-layer abrasion and scratch resistant coating and method for production thereof | ESSILOR INT | 2011-11-16 | — | — | CN | disclosed |
| US-20110058142-A1 | Optical Article Comprising a Double-Layer Abrasion and Scratch Resistant Coating and Method for Production Thereof | Essilor International (Compagnie Generale d'Otique (FR) | 2011-03-10 | — | — | US | disclosed |
| CN-101553743-A | Optical article comprising a double-layer abrasion and scratch resistant coating and method for production thereof | ESSILOR INT (FR) | 2009-10-07 | — | — | CN | disclosed |
| EP-2092377-A1 | OPTICAL ARTICLE COMPRISING A DOUBLE-LAYER ABRASION AND SCRATCH RESISTANT COATING AND METHOD FOR PRODUCTION THEREOF | ESSILOR INTERNATIONAL Compagnie Générale d'Optique (FR) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008062142-A1 | OPTICAL ARTICLE COMPRISING A DOUBLE-LAYER ABRASION AND SCRATCH RESISTANT COATING AND METHOD FOR PRODUCTION THEREOF | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2008-05-29 | — | — | WO | disclosed |