Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 17/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.55 |
| ▸ | NOS2 | P35228 | 3/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14398788 | 1.00 | GPBAR1 (0.55) | GPBAR1PRKCDNOS2KEAP1 | |
| SCHEMBL14400845 | 1.00 | GPBAR1 (0.55) | GPBAR1PRKCDNOS2KEAP1 | |
| SCHEMBL14400846 | 0.86 | TDP1 (0.56) | GPBAR1PRKCDNOS2 | |
| SCHEMBL5444459 | 0.86 | TDP1 (0.56) | GPBAR1PRKCDNOS2 | |
| SCHEMBL13351911 | 0.85 | GPBAR1 (0.64) | GPBAR1 | |
| SCHEMBL14398790 | 0.85 | GPBAR1 (0.64) | GPBAR1 | |
| SCHEMBL5442215 | 0.85 | GPBAR1 (0.64) | GPBAR1 | |
| SCHEMBL3525117 | 0.85 | GPBAR1 (0.64) | GPBAR1 | |
| SCHEMBL13754299 | 0.79 | NOS2 (0.48) | GPBAR1PRKCDNOS2KEAP1 | |
| Dihydrobetulonic Acid SCHEMBL10061167 | 0.78 | GPBAR1 (0.71) | GPBAR1PRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232577-A1 | Synthetic pentacyclic triterpenoids and derivatives of betulinic acid and betulin | ADVANCED LIFE SCIENCES, INC. (US) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232577-A1 | Synthetic pentacyclic triterpenoids and derivatives of betulinic acid and betulin | BET1, PGGT1B, BRCA1 | GPBAR1 225/4885PRKCD 1907/4885NOS2 818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.