SCHEMBL5445787

SCHEMBL5445787

CCCCCCCCCCCC(=O)NC(=S)Nc1cccc(Cl)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.72
HPGD P15428 2/20 0.72
CYP1A2 P05177 2/20 0.69
CYP3A4 P08684 2/20 0.69
CYP2C19 P33261 2/20 0.69
PKM P14618 1/20 0.63
EPHX2 P34913 3/20 0.61
EPHX1 P07099 3/20 0.60
LMNA P02545 1/20 0.58
CYP2D6 P10635 1/20 0.58
CYP2C9 P11712 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11762635 0.85 EPHX1 (0.53) ALDH1A1HPGDCYP1A2CYP3A4CYP2C19
SCHEMBL13753201 0.84 EPHX2 (0.72) ALDH1A1CYP1A2CYP3A4CYP2C19EPHX2
SCHEMBL5452444 0.81 NPY1R (0.72) ALDH1A1HPGDCYP1A2CYP3A4CYP2C19
SCHEMBL16229455 0.80 SIRT2 (0.63) ALDH1A1HPGD
SCHEMBL30125025 0.80 NPC1 (0.74) ALDH1A1HPGDCYP1A2CYP3A4CYP2C19
SCHEMBL5455510 0.80 NPC1 (0.74) ALDH1A1HPGDCYP1A2CYP3A4CYP2C19
SCHEMBL5442317 0.80 HTT (0.70) ALDH1A1HPGDEPHX1LMNANPSR1
SCHEMBL1061303 0.79 EPHX2 (0.88) ALDH1A1EPHX2EPHX1
SCHEMBL5446534 0.77 ALDH1A1 (0.66) ALDH1A1HPGDLMNANPSR1
SCHEMBL27686969 0.76 NPY1R (0.56) ALDH1A1HPGDCYP1A2CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101129295-B There is the binary initiator system of good storage stability and especially suitable for acidic system HERAEUS KULZER GMBH (DE) 2016-02-10 CN disclosed
CN-101129295-A 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems HERAEUS KULZER GMBH (DE) 2008-02-27 CN disclosed
US-20070040151-A1 Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems HERAEUS KULZER GMBH (DE) 2007-02-22 US disclosed