Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.72 |
| ▸ | NPY2R | P49146 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5442317 | 0.86 | HTT (0.70) | NPY1RNPY2RHTTALDH1A1HPGD | |
| SCHEMBL27686969 | 0.85 | NPY1R (0.56) | NPY1RNPY2RHTTALDH1A1HPGD | |
| SCHEMBL5445787 | 0.81 | ALDH1A1 (0.72) | ALDH1A1HPGDLMNANPSR1CYP1A2 | |
| SCHEMBL5463741 | 0.81 | ALDH1A1 (0.67) | NPY1RNPY2RSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL5446534 | 0.79 | ALDH1A1 (0.66) | NPY1RNPY2RHTTALDH1A1HPGD | |
| SCHEMBL17293743 | 0.75 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1HPGDKMT2ACYP1A2 | |
| SCHEMBL5451487 | 0.74 | ALDH1A1 (0.70) | NPY1RNPY2RSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL11514088 | 0.74 | NOX1 (0.63) | SMN1; SMN2HTTNOX1ALDH1A1ALOX12 | |
| SCHEMBL5448140 | 0.74 | ALDH1A1 (0.69) | SMN1; SMN2HTTALDH1A1HPGDKMT2A | |
| SCHEMBL6097065 | 0.73 | SMN1; SMN2 (0.78) | SMN1; SMN2HTTNOX1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |