Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.72 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8278749 | 0.90 | F2R (0.65) | EPHX2EPHX1MEN1ALDH1A1KMT2A | |
| SCHEMBL10969527 | 0.89 | KDM4E (0.72) | KDM4EMEN1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL28029453 | 0.85 | EPHX2 (0.57) | EPHX2EPHX1KDM4EMEN1ALDH1A1 | |
| SCHEMBL1066525 | 0.85 | EPHX2 (1.00) | EPHX2EPHX1MEN1KMT2AMAPT | |
| SCHEMBL7825915 | 0.84 | MEN1 (0.68) | EPHX2MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL1080094 | 0.84 | EGFR (0.64) | EPHX2MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL5445787 | 0.84 | ALDH1A1 (0.72) | EPHX2EPHX1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4126168 | 0.83 | RAB9A (0.67) | MEN1ALDH1A1KMT2ACYP3A4LMNA | |
| SCHEMBL11901010 | 0.83 | LMNA (0.69) | EPHX2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL15480411 | 0.83 | HDAC1 (0.69) | EPHX2KDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021104506-A1 | CYCLIC SULFONE COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 中国医学科学院药物研究所 | 2021-06-03 | — | — | WO | disclosed |
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |